Administrative and Engagement Core

尼日利亚在应对癌症控制方面正处于十字路口。一方面，这个国家仍然是 日益严重的癌症危机。另一方面，有现有的指导方针(例如，国家癌症控制中心 尼日利亚卫生部的计划2，世界在尼日利亚消除宫颈癌的成本计算 卫生组织，3全社会消除宫颈癌指南，4和最近的国家战略 癌症控制疫苗框架)。5这些加快了步伐并创造了新的机会 以实现该国降低尼日利亚癌症发病率和死亡率的愿景。因此，为了 支持传统临床服务内外的新型伙伴关系，包括社区环境和 非卫生部门组织，我们建议美国-尼日利亚癌症控制中心研究 实施科学与公平(C3-RISE)管理和参与核心(AEC)。我们最重要的是 目标是改善尼日利亚的癌症控制，并与以下机构合作对公共卫生产生持续影响 关键利益相关者。我们拟建的U54中心汇集了一个跨学科的研究团队，以有意义地 与关键利益攸关方合作，包括个人、社区以及地方和国家卫生部。 U54计划将促进尼日利亚实施科学(IS)计划，以优化实施 尼日利亚癌症控制工作的疫苗。AEC将负责整体管理， 协调、管理该中心并与美国国立卫生研究院进行沟通。它将促进协作 在研究人员和关键利益攸关方之间建立联系，并为公平实施 循证疫苗(即宫颈癌和乙肝的人乳头瘤病毒(HPV)疫苗) 用于癌症控制的疫苗)。我们还将为尖端技术制定全国和全球标准 参与式研究方法是在资源有限的情况下加快采用的研究方法， 尼日利亚有效癌症控制干预措施的适应性和可持续性。我们的具体目标是：1) 使用敏捷的方法协调中心范围内活动的项目管理；2)作为一个社区 使用众包方法在尼日利亚的IS接洽中心；以及3)评估中心的里程碑和 总体进步。通过提供可促进中心范围的通信、运营、 作为社区外展和评估的一部分，AEC将作为一个中央协调中心，加强 降低癌症发病率和死亡率，同时促进信息系统在公平癌症控制方面的作用 尼日利亚。

Nigeria is at a crossroads in its cancer control response. On the one hand, the country remains an epicenter of a growing cancer crisis. On the other hand, there are existing guidelines (e.g., the National Cancer Control Plan2 by the Nigerian Ministry of Health, the Costing for Cervical Cancer Elimination in Nigeria by the World Health Organization,3 a Society-wide guideline for cervical cancer elimination,4 and a recent National Strategic Framework on vaccines for cancer control).5 These have accelerated the tempo and created new opportunities to achieve the country's vision for reducing the incidence and mortality of cancer in Nigeria. As a result, to support novel partnerships within and beyond traditional clinical services, including in community settings and non-health sector organizations, we propose the US-Nigerian Cancer Control Center for Research on Implementation Science and Equity (C3-RISE) Administration and Engagement Core (AEC). Our overarching goal is to improve cancer control in Nigeria and exert a sustained impact on public health in partnership with key stakeholders. Our proposed U54 Center brings together a transdisciplinary research team to meaningfully collaborate with key stakeholders, including individuals, communities, and local and state ministries of health. The U54 program will foster a Nigerian implementation science (IS) program to optimize the implementation of vaccines for cancer control efforts in Nigeria. The AEC will be responsible for the overall administration, coordination, and management of the Center and communication with the NIH. It will foster collaboration between researchers and key stakeholders and provide critical infrastructure for equitable implementation of evidence-based vaccines (i.e. human papillomavirus (HPV) vaccines for cervical cancer and hepatitis B (HepB) vaccines for liver cancer) for cancer control. We will also set a national and global standard for cutting-edge participatory IS research approaches9 in a resource-constrained setting that accelerates the adoption, adaptation, and sustainability of effective cancer control interventions in Nigeria. Our specific aims are: 1) To coordinate project management of the center wide-activities using agile methods; 2) To serve as a community engagement hub for IS in Nigeria using crowdsourcing methods; and 3) To evaluate Center's milestones and overall progress. By providing an infrastructure that facilitates Center-wide communications, operations, community outreach and evaluation, the AEC will serve as a central focal point to reinforce the overall vision of reducing the incidence and mortality of cancer while advancing the role of IS for equitable cancer control in Nigeria.