Indiana Clinical and Translational Sciences Institute

项目摘要/摘要 印第安纳州临床和转化科学研究所(Indiana CTSI)成立于2008年，当时是全州范围内的 三所研究型大学(印第安纳州、普渡大学)合作加速临床和转化性研究 和巴黎圣母院，与合作伙伴医疗保健系统和提供者、社区和患者利益相关者、当地 基金会、企业和政府合作伙伴。印第安纳州CTSI的使命是将印第安纳州的 最聪明的人解决最紧迫的健康挑战，作为全州临床和 在印第安纳州、全国乃至更远的地方进行翻译研究并改善人类健康。印第安纳州CTSI 促进协作研究环境，提供资源和服务，以进行最高质量的 临床和翻译研究，提供教育和培训计划，以建立强大的翻译 劳动力，使我们的社区成为所有级别的合作伙伴，通过以下方式确定并消除研究障碍 翻译科学的方法，并作为国家CTSA网络的模范成员。这个 CTSI计划通过五个具体目标完成其使命：目标1.加快培训和研究 全州有机会创建一支多元化且值得信赖的翻译研究队伍，以证明 通过有效的沟通，团队科学和真实的尊重，责任和文化谦逊 利益相关者的参与。目标2.丰富和整合我们的患者、医疗保健、企业、社区、 以及政府机构合作伙伴，以更好地接触印第安纳州未得到充分服务的人口并赋予他们权力， 重点关注健康状况最差的地区和群体。目标3.加强对i-CTSI方案的获取和 促进和加快有影响力的临床和转化性研究的服务，这些研究具有创新性、包容性、 协作性的、合乎道德的、有效地传播和实施基于证据的干预措施 州政府。目标4.确定障碍，创建解决方案，并传播临床最佳实践的新方法 通过社区和利益相关者的参与、试点资金和值得信赖的 整合的翻译研究生态系统。目标5.利用我们的全州信息学平台和创新 与全州医疗系统协作，协调不同数据源的分析能力 并有意将不同人群纳入其中，以促进健康公平。在2030年，在这七年结束的时候- 年续签资助期，我们预计i-CTSI将通过以下方式改变我们的全州研究生态系统 在我们的伙伴关系、劳动力发展和研究中刻意关注多样性和包容性 订婚。我们将加快创新，迅速将证据付诸实践，以推动 健康公平。

PROJECT SUMMARY/ABSTRACT The Indiana Clinical and Translational Sciences Institute (Indiana CTSI) was created in 2008 as a statewide partnership to accelerate clinical and translational research by the three research universities, Indiana, Purdue and Notre Dame, with partner health care systems and providers, community and patient stakeholders, local foundations, corporate and government partners. The mission of the Indiana CTSI is to bring together Indiana's brightest minds to solve the most pressing health challenges by serving as the statewide catalyst for clinical and translational research and improve human health across Indiana, the nation and beyond. The Indiana CTSI fosters a collaborative research environment, provides resources and services to conduct the highest-quality clinical and translational research, offers education and training programs to build a robust translational workforce, engages our community as a partner at all levels, identifies and removes barriers to research through translational science approaches, and functions as an exemplary member of the national CTSA network. The CTSI plans to accomplish its mission through five Specific Aims: Aim 1. Accelerate training and research opportunities across the state to create a diverse and trusted translational research workforce that demonstrates respect, responsibility, and cultural humility through effective communication, team science and authentic stakeholder engagement. Aim 2. Enrich and integrate our network of patient, health care, corporate, community, and government agency partners to better engage and empower underserved populations across Indiana, focusing on regions and groups with poorest health outcomes. Aim 3. Enhance access to I-CTSI programs and services to facilitate and expedite impactful clinical and translational research that is innovative, inclusive, collaborative, and ethical, and effectively disseminates and implements evidence-based interventions across the state. Aim 4. Identify barriers, create solutions, and disseminate novel approaches for best practices of clinical and translational science through community and stakeholder engagement, pilot funding, and a trustworthy and integrated translational research ecosystem. Aim 5. Leverage our statewide informatics platform and innovative analytic capabilities to harmonize disparate data sources in collaboration with health systems across the state and with deliberate inclusion from diverse populations to advance health equity. In 2030, at the end of this seven- year renewal funding period, we envision the I-CTSI will transform our statewide research ecosystem with deliberate attention to diversity and inclusion in our partnerships, workforce development and research engagement. We will accelerate innovation and rapidly implement evidence into practice in order to advance health equity.