2023 Physiology, Biology and Pathology of Phosphate GRC

2023年磷酸盐GRC的生理学、生物学和病理学

• 批准号: 10608802
• 负责人: Sharon M Moe
• 金额: $ 0.5万
• 依托单位: GORDON RESEARCH CONFERENCES
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-02-10 至 2024-02-09
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10608802
• 关键词: Advanced Development; Aging; Area; Attention; Basic Science; Biological Process; Biology; Cell physiology; Cells; Clinical Sciences; Collaborations; Communication; Complex; Discipline; Disease; Endocrine; Ensure; Environment; Equilibrium; Evaluation; Feedback; Fostering; Friends; Functional disorder; Future; Goals; Growth; Health; Homeostasis; Hour; Interdisciplinary Study; Intestines; Kidney; Kidney Diseases; Measurement; Mentors; Metabolism; Methods; Minerals; Modeling; Molecular; Oral; Organ; Parathyroid gland; Participant; Pathologic; Pathology; Pathway interactions; Physiology; Postdoctoral Fellow; Recording of previous events; Regulation; Research; Research Personnel; Science; Scientist; Senior Scientist; Signal Transduction; Social Interaction; Societies; System; Systems Biology; Translational Research; Woman; absorption; bone; career; career development; clinical care; design; disadvantaged background; falls; improved; innovation; inorganic phosphate; interdisciplinary collaboration; meetings; new therapeutic target; next generation; novel therapeutic intervention; nutrition; posters; pre-doctoral; programs; senior faculty; success; symposium; tool; translational pipeline; uptake

Project Summary/Abstract The 2023 Gordon Research Conference (GRC) “Physiology, Biology and Pathology of Phosphate” will provide cutting edge science and stimulate inter-disciplinary collaborations to facilitate a better understanding of the complexity of normal and pathologic phosphate regulation. This integration, or full understanding, or the systems biology that control this mineral is needed if we are to understand both normal physiology and regulation in different disease states. Investigators that study intestine, kidney, parathyroid glands and bone, each with both unique and common pathways for sensing, signaling, and responding to changes in phosphate concentrations will come together to share new discoveries. These scientists do not normally interact given the diversity of organs involved, and thus this GRC will provide a forum that facilitates scientific exchange among diverse scientists from around the world, working across the translational spectrum and from all career stages. The number of overall participants will be capped at 200 to ensure an environment conducive to friendly exchange, social interactions that facilitate collaborations, and conversations that propel the field forward. The program will have 25 talks organized into nine morning and evening sessions entitled 1) Overview of Phosphate in Health and Disease, 2) Organs Contributing to Phosphate Homeostasis and Endocrine Regulators, 3) Disorders of Phosphate Homeostasis, 4) Organ Crosstalk in the Regulation of Phosphate Balance, 5) Phosphate Sensing, Uptake, Signaling and Effects in cells, 6) Pathologic Effects of Phosphate on Cells, 7) Biology of Phosphate Containing Complexes 8) Measurements and Models, 9) The Intestinal Environment and Regulation of Phosphate Absorption. In each session, selected posters will be presented orally and there will be a facilitated discussion. Poster sessions will be held each day and purposely place investigators from different fields adjacent to each other to facilitate conversation and exchange of methods and ideas to build collaborations. The meeting will also have a “power hour” to focus on the challenges facing women in science, moderated by Co-Chairs and GRC staff. Additional small group opportunities that engage pre and post docs with senior faculty will be organized to provide career advice, identify potential mentors or sponsors, and facilitate collaborations. In summary, this inaugural GRC focusing on the cellular effects and regulation of phosphate homeostasis will facilitate cross-disciplinary collaborations and encourage trainees that the future of this field is exciting.

项目摘要/摘要 2023年戈登研究会议(GRC)《磷酸盐的生理学、生物学和病理学》将提供 尖端科学和促进跨学科合作，以促进对 正常和病理性磷酸盐调节的复杂性。这种整合，或完全理解，或系统 如果我们要了解这种矿物质的正常生理和调节，就需要控制这种矿物质的生物学 不同的疾病状态。研究肠、肾、甲状旁腺和骨骼的研究人员 感知、发送信号和响应磷酸盐浓度变化的独特而常见的途径 将聚在一起分享新的发现。这些科学家通常不会互动，因为 因此，这个GRC将提供一个论坛，促进不同国家之间的科学交流 来自世界各地的科学家，在翻译领域和职业生涯的各个阶段工作。这个 总参加人数上限为200人，以确保有利于友好交流的环境， 促进协作的社交互动，以及推动该领域向前发展的对话。该计划将 将25个讲座组织成9个上午和晚上的会议，题为1)磷酸盐在健康中的概述 和疾病，2)有助于磷酸盐稳态和内分泌调节的器官，3)疾病 磷酸盐稳态，4)磷酸盐平衡调节中的器官串扰，5)磷酸盐传感， 细胞内摄取、信号及效应，6)磷酸盐对细胞的病理效应，7)磷酸盐的生物学 含有络合物8)测量和模型，9)肠道环境和调节 磷酸盐吸收。在每一次会议中，选定的海报将被口头介绍，并将有促进的 讨论。每天将举行海报会议，并有意将来自不同领域的调查人员安排在 相互促进对话和交流建立协作的方法和想法。这次会议 还将在联席主席和联合主席的主持下，举办一个关注女性在科学领域面临的挑战的“权力小时” GRC工作人员。与资深教师接触博士后和博士后的其他小组机会将是 组织提供职业建议，确定潜在的导师或赞助商，并促进合作。在……里面 总结，这个首届GRC专注于细胞效应和磷酸盐稳态的调节，将 促进跨学科合作，鼓励学员相信这一领域的未来是令人兴奋的。