Mwanza-Tanzania Research Training Program in HIV Clinical Investigation

该计划将加强以病人为导向的艾滋病毒临床调查培训的医生，科学家， 其他杰出的临床医生在坦桑尼亚西北部的姆万扎。该计划建立在20年的 伙伴机构的协作和能力建设。坦桑尼亚的主要研究机构将 姆万扎干预试验单位（MITU）是坦桑尼亚国家医学研究所的一个单位， 研究（NIMR）。MITU成立于2006年，是NIMR和伦敦学校的合作项目 卫生和热带医学部（LSHTM），以加强坦桑尼亚的艾滋病毒干预研究。MITU 与同样位于姆万扎的威尔布甘多医学院密切合作。Weill Bugando成立于2003年，为坦桑尼亚西北部培训医生。MITU和Weill Bugando 威尔康奈尔医学院自成立以来一直与他们合作。 这项研究培训计划旨在填补姆万扎的一个关键空白：坦桑尼亚医生的需求， 在以病人为导向的艾滋病毒临床调查方面接受严格培训。我们使用NIH对临床的定义 研究是指直接与I、II期或III期患者个体或患者群相互作用的研究， 临床试验、实用性试验或形成性流行病学或行为学研究，为临床试验做准备。 审判培训计划的目标是：1.增加临床研究者的数量， MITU，从而提高艾滋病毒临床调查的机构能力2.建立Weill Bugando/MITU 作为艾滋病临床研究的可持续培训中心。最终目标是预防新的艾滋病毒 艾滋病毒感染，提供有效的艾滋病毒护理，并改善坦桑尼亚和东非的艾滋病毒结果。 我们将长期培训十五名优秀的临床科学家，以患者为导向开展艾滋病毒 临床研究我们将主要培训医生，但也将培训特殊的其他临床医生（药学博士， DMD）。我们将培养10名博士和5名硕士学位候选人。坦桑尼亚受训人员将受益于参与 在艾滋病毒调查的五个协同领域，包括艾滋病毒预防和 疫苗研究、艾滋病毒检测和治疗的实施、妇女健康、与艾滋病毒有关的合并感染，以及 艾滋病毒和心血管疾病。我们还将加强在韦尔临床研究博士课程 Bugando通过引入4个新的临床研究研究生课程。威尔·康奈尔承诺 机构资金，使4个最好的博士毕业生可以有2年的博士后任命， MITU的研究科学家在接受Fogarty培训后。在5年培训计划结束时，MITU将拥有 一个临床研究骨干和更大的深度和广度的外部资助的艾滋病毒患者为导向的 research. MITU/Weill Bugando将成为东非艾滋病毒临床研究人员的培训中心。

The program will strengthen patient-oriented HIV clinical investigation training of physician-scientists and other exceptional clinicians in Mwanza, in northwestern Tanzania. The program builds upon two decades of collaboration and capacity building by the partner institutions. The primary research institution in Tanzania will be the Mwanza Intervention Trials Unit (MITU), which is a unit of Tanzania’s National Institute for Medical Research (NIMR). MITU was established in 2006 as a collaboration between NIMR and the London School of Hygiene and Tropical Medicine (LSHTM) to strengthen HIV interventional research in Tanzania. MITU collaborates closely with the Weill Bugando School of Medicine, which is also located in Mwanza. Weill Bugando was established in 2003 to train physicians for northwestern Tanzania. MITU and Weill Bugando have collaborated with Weill Cornell Medical College since their founding. This research training program aims to fill a critical gap in Mwanza: the need for Tanzanian physicians with rigorous training in patient-oriented HIV clinical investigation. We use the NIH definition of clinical investigation as research which directly interacts with individual patients or clusters of patients in Phase I, II, or III clinical trials, pragmatic trials, or formative epidemiologic or behavioral research in preparation for clinical trials. The goals of the proposed training program are: 1.To increase the number of clinical investigators at MITU and thereby increase institutional capacity for HIV clinical investigation 2. Establish Weill Bugando/MITU as a sustainable training center for HIV clinical investigation. The ultimate goal is to prevent new HIV infections, provide effective HIV care, and improve HIV outcomes in Tanzania and East Africa. We will provide long-term training to fifteen outstanding clinician scientists to conduct patient-oriented HIV clinical investigation. We will primarily train physicians but will also train exceptional other clinicians (PharmD, DMD). We will train 10 PhDs, and 5 MS degree candidates. Tanzanian trainees will benefit from participation in 17 active research projects in five synergistic areas of HIV investigation including HIV prevention and vaccine research, implementation of HIV testing and treatment, women’s health, HIV related co-infections, and HIV and cardiovascular disease. We will also strengthen the PhD program in clinical investigation at Weill Bugando by introducing 4 new graduate courses in clinical investigation. Weill Cornell is committing institutional funds so that 4 of the best PhD graduates can have 2-year post-doctoral appointments as MITU research scientists after their Fogarty training. At the end of the 5-year training program, MITU will have a cadre of clinical investigators and a greater depth and breadth of externally funded HIV patient-oriented research. MITU/Weill Bugando will be a training hub for HIV clinical investigators in East Africa.