UNC Center for Environmental Health and Susceptibility

摘要 北卡罗来纳州环境、健康和敏感性中心(CEHS)的主题是 关于环境健康敏感性的跨学科研究，以改善北卡罗来纳州的公共健康。这个 该中心鼓励和促进基础研究人员、公共卫生科学家和 临床医生产生影响很大的发现，改善公共健康。翻译研究的三个焦点 支持的领域包括：环境癌症、心肺疾病和发育疾病。健康状况 差距和北卡罗来纳州的普遍风险敞口是贯穿各领域的主题。战略愿景得到落实 由负责监督设施核心、评估创新试点项目并为其提供资金的管理核心机构、赞助商 研讨会和座谈会，支持职业发展，与中心成员沟通，准备 预算、报告和时事通讯，跟踪出版物和拨款建议。该中心有两个设施核心 为人类研究提供便利并提供科学支持。综合健康科学设施核心(IHSFC) 鼓励新的临床和基于人群的研究，并将成员与丰富的现有研究联系起来 和数据。IHSFC还提供人体研究方面的专业知识，包括为 参与者参与和生物样品处理。分子分析与统计支持(MASS) 设备核心提供从研究设计到数据采集再到分析的全方位科学支持。穿过 无预约诊所、个人咨询、培训和方法开发资金，由群众核心提供 质谱学、翻译组织病理学和尖端基因组学的专业知识和仪器， 同时还在研究设计、数据分析、培训和方法方面提供计算和统计支持 发展。集成的科学支持模式确保在曝光科学、成像和 组学研究，我们中心的优势。社区参与核心(CEC)将CEHS研究人员联系在一起 与社区伙伴合作，促进多方向沟通，确保与国家的广泛相关性， 这两点对CEHS的翻译目标都至关重要。科学和参与项目都是 由优先考虑初级教员的竞争性试点项目项目支持。CEHS积极指导和 培养初级和中级职业调查员的领导力，培养下一代环境调查人员 健康研究人员。通过我们的利益攸关方咨询委员会和外部咨询委员会 接收关于北卡罗来纳州社区关注的环境暴露的意见和中心的反馈 有效性。CEHS的目标与NIEHS战略计划一致，为北卡罗来纳州的公共卫生服务 和国家的战略科学活动和社区参与。

ABSTRACT The theme of the UNC Center for Environmental Health and Susceptibility (CEHS) is translating interdisciplinary research on environmental health susceptibility to improve public health in North Carolina. The Center encourages and facilitates collaborations among basic researchers, public health scientists, and clinicians to generate high impact discoveries that improve public health. Three translational research focus areas are supported: environmental cancer, cardiopulmonary disease, and developmental disease. Health disparities and prevalent North Carolina exposures are cross-cutting themes. The strategic vision is implemented by the Administrative Core, which oversees facility cores, evaluates and funds innovative pilot projects, sponsors seminars and symposia, supports developing careers, communicates with Center membership, prepares budgets, reports and newsletters, and tracks publications and grant proposals. The Center has two facility cores that facilitate human studies and provide scientific support. The Integrated Health Sciences Facility Core (IHSFC) encourages new clinical and population-based studies and connects members to a wealth of existing studies and data. The IHSFC also provides expertise in human studies, including professional staffing support for participant engagement and biospecimen processing. The Molecular Analysis and Statistical Support (MASS) facility core provides full service scientific support, from study design to data acquisition to analytics. Through walk-in clinics, individual consultation, training and methods development funding, the MASS core provides expertise and instrumentation for mass spectrometry, translational histopathology, and cutting edge genomics, while also providing computational and statistical support with study design, data analysis, training and methods development. An integrated scientific support model ensures excellence in exposure science, imaging, and omics studies, strengths of our Center. The Community Engagement Core (CEC) connects CEHS researchers with community partners, facilitating multidirectional communication and ensuring broad relevance to the State, both of which are critical to the translational goals of CEHS. Both scientific and engagement projects are supported by a competitive Pilot Projects program that prioritizes junior faculty. CEHS actively mentors and cultivates leadership of junior and mid-level career investigators to train the next generation of environmental health researchers. Through our Stakeholder Advisory Board and External Advisory Board the UNC-CEHS receives input on environmental exposures of concern in North Carolina communities and feedback on Center effectiveness. With goals aligned to the NIEHS strategic plan, CEHS serves the public health of North Carolina and the nation with strategic scientific activities and community engagement.