Third Coast Center For AIDS Research

项目总结 第三海岸CFAR：总体 第三海岸艾滋病研究中心(TC CFAR)的广泛、长期的使命是利用我们的 跨学科协作，推动翻译领域的转型进步 从发现到实施有效的干预措施--并结束艾滋病毒。许多本地资源位于 西北大学(UC)、芝加哥大学(UC)和社区合作伙伴 将继续承担这一使命。允许资助的研究基地(FRB) 从2014财年到2018财年，增长了47%，项目变得更加跨学科。灵活和 机会主义战略规划(行政核心，AC)和种子资金的强劲增长 和指导计划(由发展核心，DC)导致了这些成功，并选择 将特定的、高度优先的艾滋病毒研究主题作为第二任期的重点。制度支撑力度加大。 总体科学目标也是基于3个具有用户的科学核心中的每一个来选择的 基础资源和专家资源，在每个目标上都有优势。这些核心中的每一个也都致力于扩展 将他们的资源和专业知识提供给自己领域之外的研究人员，从而帮助建立 合作。以下总体目标建立在我们坚实的基础上，并将指导每个科学 CORE与AC和DC协调一致，协同推进消灭艾滋病毒所需的科学。 总体目标1：继续和扩大合作研究，这将减缓并最终停止 通过改进艾滋病毒预防和护理的连续性，预防艾滋病毒流行。 总体目标2：增进对加速衰老相关疾病(非艾滋病)的认识 合并症)，尽管抑制了艾滋病毒病毒血症。 总目标3：加速发现和推动变革性科学创新的发展 这将改善艾滋病毒携带者的艾滋病毒预防和治疗。

PROJECT SUMMARY THIRD COAST CFAR: OVERALL The broad, long-term mission of the Third Coast Center for AIDS Research (TC CFAR) is to use our trans-disciplinary collaborations to power transformational advances across the translational spectrum from discovery to implementation of effective interventions - and end HIV. Many local resources at Northwestern University (UC), the University of Chicago (UC), and community partners have been, and will continue to be, brought to bear on this mission. The allowable Funded Research Base (FRB) increased by 47%, and projects became more trans-disciplinary, from FY14 to FY18. Nimble and opportunistic strategic planning (by the Administrative Core, AC) and robust growth in seed funding and mentoring programs (by the Developmental Core, DC) led to those successes, and to choosing specific, high-priority HIV research topics as foci for a second term. Institutional support has increased. The Overall scientific aims were also chosen based on each of the 3 scientific Cores having a user base and expert resources with strengths on each aim. Each of these Cores has also worked to extend their resources and expertise to researchers outside their own domains, and thereby helped build collaborations. The following Overall aims build on our solid foundation, and will direct each scientific Core, in concert with the AC and the DC, to synergistically advance the science needed to end HIV. Overall Aim 1: To continue and expand collaborative research that will slow, and eventually stop, the HIV epidemic by improving continuums of HIV prevention and care. Overall Aim 2: To advance understanding of accelerated aging-related illnesses (non-AIDS comorbidities) that occur despite suppression of HIV viremia. Overall Aim 3: To speed discovery and empower development of transformative scientific innovations that will improve HIV prevention and treatment for persons living with HIV.