Summer Medical student Aging and Alzheimer disease Research Training (SMAART) program

摘要/摘要： 阿尔茨海默病和相关痴呆症(ADRD)是一种公共健康危机， 具有高质量培训和专业知识的熟练临床医生和调查人员的数量，以提供护理和 开展翻译研究。培养新一代内科科研人员具有 丰富的知识和技能，包括了解基础知识(遗传学、分子和细胞生物学、 神经科学)、患者层面(临床护理、神经心理学、液体生物标记物、神经成像、流行病学)、 和交叉(生物统计学、伦理学)的研究设计和方法。因此，我们建议的SMAART T35 该计划将扩大具有研究经验的医学生的渠道，激励新的内科科学家 专注于ADRD领域的职业生涯。熟练的ADRD翻译内科科学家的可获得性很低 对国家ADRD研究议程构成威胁。因此，在此T35申请中，我们建议 让MD学生参与研究、指导、出版、职业发展和领导力方面的工作。 通过我们在多学科翻译ADRD研究方面的领先专业知识，我们的目标是加强 通过以下三个具体目标实现内科科学家的多样性和可获得性：1)指导冠军 通过提供由杰出领导力和监督组成的综合计划来实现职业发展 在所有层面上。2)创建灵活创新的课程，既强调核心又强调高级 临床、翻译和基础科学方面的能力3)最大限度地获得夏季指导和 研究培训(SMAART)计划。通过正式签到和ADRD主题期刊俱乐部，实习生 将得到项目主管的指导和支持。该计划将对学生进行纵向跟踪 通过医学院的四年学习，鼓励继续参与研究活动。

Summary/Abstract: Alzheimer's disease and related dementias (ADRD) is a public health crisis compounded by the insufficient number of skilled clinicians and investigators with high quality training and expertise to provide care and conduct translational research. It is vital to foster a new generation of physician researchers that possess a diverse array of knowledge and skills, including understanding basic (genetics, molecular and cellular biology, neuroscience), patient level (clinical care, neuropsychology, fluid biomarkers, neuroimaging, epidemiology), and cross cutting (biostatistics, ethics) research design and methods. Thus our proposed SMAART T35 program will grow the pipeline of medical students with research experiences inspiring new physician scientists to focus their careers in the ADRD space. The low availability of skilled ADRD translational physician scientists represents a threat to the national ADRD research agenda. Therefore, in this T35 application we propose to engage MD students in hands on research, mentoring, publishing, career development and leadership. Through our leadership expertise in multidisciplinary translational ADRD research we aim to enhance the diversity and availability of physician scientists through these three specific aims: 1) Champion mentored career development by providing an integrated program that consists of outstanding leadership and oversight at all levels. 2) Create a flexible and innovative curriculum that emphasizes both core and advanced competencies in clinical, translational, and basic science 3) Maximizing access to Summer Mentoring and Research Training (SMAART) Program. Through formal check ins and ADRD themed journal clubs, trainees will receive guidance and support from the Program directors. The program will longitudinally track students through the four years of medical school encouraging continued engagement in research activities.