DRUG ABUSE AND OTHER DEVIANT ADAPTATIONS TO STRESS

这是一个（竞争性延续）ADAMHA研究的请求 科学家奖（RSA）。广泛的目标包括研究， 职业提升和指导目标。研究目的是 估计理论上知情的模型，指定（1） 药物滥用模式的心理社会前因和后果 以及其他对压力的异常适应， 在整个生命周期中， 在青春期早期和生命的第四个十年（30多岁）之间， 和（2）跨代的连续性和不连续性（ 群体及其青少年儿童）的药物滥用模式， 其他异常适应，以及它们的相关性，观察到在一个 两人的发育阶段（青春期早期）相当 代第一组模型的数据来自家庭 采访了一组年龄在305岁左右的受试者， 在他们20多岁的中后期（N = 6，089）和之前接受采访， 在七年级的时候模型指定直接和 早期生命阶段对后期阶段的间接影响，并详细说明 缓和影响性质的情况。越轨 模式包括暴力，自我毁灭行为，功能性 精神疾病，一系列犯罪活动，以及 违反有关收养的规范性规定， 传统社会角色的表现，以及 吸毒这些模式被不同地建模为前因或 彼此的后果。其他前因和后果 药物滥用和其他异常适应包括态度和 在不同的社会环境中， 关系情境，慢性角色紧张，归因社会 身份，应对方式，生活事件，个人和 人际资源，同伴交往，自我感觉， 价值观第二组模型的数据来自家庭 与已经达到的同龄儿童的访谈 父母在青春期早期首次接受采访时的年龄 或者在研究过程中他们达到那个年龄时。的 模型将考虑连续性和不连续性之间 在青春期早期，通过指定中介， 影响和共同的前因经验。模特们将在 估计使用结构等多元技术。 研究技能将通过研究新的方法来提高， 多变量分析，并与其他工作人员合作 纵向项目。指导活动包括以下指导： 受雇于项目和研讨会的研究生 药物滥用的物质和研究方法。

This is a (competing continuation) request for an ADAMHA Research Scientist Award (RSA). The broad objectives include research, career enhancement, and mentoring goals. The research objective is to estimate theoretically informed models that specify (1) the psychosocial antecedents and consequences of patterns of drug abuse and other deviant adaptations to stress and the constructs that moderate these relationships, for a cohort over the life span between early adolescence and the fourth decade of life (mid 30s), and (2) continuities and discontinuities across generations (the cohort and their adolescent children) of patterns of drug abuse and other deviant adaptations, and their correlates, observed at a comparable developmental stage (early adolescence) for the two generations. Data for the first set of models are from household interviews with a cohort of subjects in their mid 305 who were interviewed during their mid-to-late 20s (N=6,089) and, prior to that, during the seventh grade. The models specify direct and indirect effects of earlier life stages on later stages and specify the circumstances that moderate the nature of the effects. Deviant patterns include violence, self-destructive behaviors, functional psychiatric disorders, a range of criminal activities, and violation of normative prescriptions regarding the adoption and performance of conventional social roles, as well as patterns of drug abuse. These patterns are variously modeled as antecedents or consequences of each other. Other antecedents and consequences of drug abuse and other deviant adaptations include attitudes and behavioral responses of significant others in various social- relational contexts, chronic role strain, ascribed social identities, modes of coping, life events, personal and interpersonal resources, peer associations, self-feelings, and values. Data for the second set of models are from household interviews with the children of the cohort who have already reached the age the parent was when first interviewed in early adolescence or at the time they reach that age in the course of the study. The models will account for continuities and discontinuities between the generations during early adolescence by specifying mediating influences, and common antecedent experiences. The models will be estimated using structural among other multivariate techniques. Research skills will be enhanced by studying new methods of multivariate analysis and by collaboration with staffs of other longitudinal projects. Mentoring activities include guidance of graduate students who are employed on the project and in seminars in the substance and methods of research on substance abuse.