RESPIRATOR TOLERANCE

呼吸器耐受性的决定因素似乎是 多因素。这项研究将利用人类小组方法来 评估呼吸器和Will的综合影响 检查几种类型的呼吸器负载的影响以获得 对工人耐受机制的理解 使用呼吸器。人类受试者小组将参加一项 一系列研究。结果指标将包括生理学指标 变量(例如，呼吸计时、通风、呼吸功)、 主观容忍度(通过视觉模拟标尺测量)和工作 表演能力。对负荷的心理生理敏感性(两者 电阻和压力偏差)也将被测量。研究将会 在实验室环境下，在规定的野外课程中进行 (在此期间，受试者可以自行调整速度)，以及在工作场所。 呼吸器替代负荷和实际呼吸器将是 就业，并将雇用几种类型的锻炼。这个 预测器之间的相互关系(例如， 呼吸器负荷、用力类型)和结果措施 评估以确定呼吸器影响的机制和 开发准确和合理简单的人体面板方法 来测试呼吸器。实验设计允许复杂 通过让每个受试者参与一系列研究来进行分析 并随着时间的推移重复某些实验条件。 分项目将解决更多的具体问题。其影响 生理上的压力偏置(就像许多SCBA发生的那样)， 主观性、工作表现和肺容量测量将 测试过。一群自我认同的工人，他们特别 不能容忍呼吸器的人会参与进来。呼吸器的使用 在模拟的“紧急使用”情况下，将在 与更常规的使用相比。

The determinants of respirator tolerance appear to be multifactorial. This study will utilize a human panel method for the assessment of the integrated effects of respirators and will examine the effects of several types of respirator loads to gain understanding of the mechanisms by which workers tolerate respirator use. Panels of human subjects will participate in a series of studies. Outcome measures will include physiologic variables (e.g., respiratory timing, ventilation, ventilatory work), subjective tolerance (measured by visual analog scales), and work performance ability. Psychophysiologic sensitivity to loads (both resistive and pressure bias) will be measured as well. Studies will be performed in a laboratory setting, in a prescribed field course (during which the subject may self pace), and at worksites. Respirator surrogate loads and actual respirators will be employed, and several types of exercise will be employed. The inter-relationships between and among the predictor (e.g., respirator load, exertion type) and outcome measures will be assessed to define mechanisms of respirator effects and to develop accurate and reasonably simple means for human panels to test respirators. The experimental design permits complex analyses by having each subject participate in a series of studies and by repeating certain experimental conditions over time. Subprojects will address additional specific problems. The effects of pressure biasing (as occurs with many SCBA's) upon physiologic, subjective, work performance, and lung volume measures will be tested. A group of self-identified workers who are particularly intolerant of respirators will participate. The use of respirators in simulated "emergency use" situations will be assessed in comparison to more routine use.