Respirator Effects in Impaired Workers

呼吸器对受损工人的影响

• 批准号: 7265129
• 负责人: PHILIP I. HARBER
• 金额: $ 9.16万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-07-15 至 2009-07-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7265129
• 关键词: Respirator; Effects; Impaired; Workers

In the field of Occupational Safety and Health, respirators (respiratory personal protective equipment, RPPE) have been widely used in industry. More recently, the possibility of bioterrorism and/or epidemics as well as the perception of risk increase the likelihood of much more widespread respirator use. Persons with mild respiratory impairments or individuals who develop mild respiratory impairments as a consequence of terrorism and/or epidemic may be required to use respirators rather than being excluded from manyjobs. This project will extend prior research about respirator effects in relatively healthy individuals to personswith mild respiratory impairments. Four groups of subjects will be studied: normal, COPD, chronic rhinitis, asthma. Each subject will be studied in a controlled exercise laboratory using respirator surrogateloads (inspiratory resistance, expiratory resistance, dead space). In addition, each will be studied during simulated "real world" work of a sedentary or moderate exertion level using an N95 and a full face mask respirator. Measures will include physiologic parameters, subjective ratings, and estimates of proper utilization. Over three years, approximately 140 subjects will participate. The project should characterize the response patterns of these individual groups as well as delineate the effects of different components of respirator loads. The information may be useful for policy establishment (e.g., shelter in place vs. respirator use), designing better respirators, and worker selection/counseling.

在职业安全和健康领域，呼吸器（呼吸个人防护设备） 在工业上得到了广泛的应用。最近，生物恐怖主义和/或流行病以及 对风险的认识增加了更广泛使用呼吸器的可能性。轻度 呼吸道损伤或由于以下原因而出现轻度呼吸道损伤的个体 恐怖主义和/或流行病可能被要求使用反恐怖主义者，而不是被排除在许多工作之外。 该项目将把先前关于呼吸器对相对健康个体的影响的研究扩展到患有 轻微的呼吸障碍将研究四组受试者：正常、COPD、慢性鼻炎、 哮喘每个受试者将在受控运动实验室中使用呼吸器替代负荷进行研究 （吸气阻力、呼气阻力、死腔）。此外，每一个都将在模拟过程中进行研究。 “真实的世界”工作的久坐或中度劳累水平使用N95和全面罩呼吸器。 测量将包括生理参数、主观评级和适当使用的估计。超过 三年后，大约有140名受试者将参与研究。该项目应描述应对措施的特点 这些个体群体的模式以及描述呼吸器的不同组件的影响 载荷该信息可能对策略建立有用（例如，在适当位置提供庇护与使用呼吸器）， 设计更好的呼吸器，以及工人选择/咨询。