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中文摘要
翻译
CCR协作性生物信息学资源(CCBR)是一个组织保护伞,它为CCR研究人员提供了一种机制,以获得多种不同类型的生物信息学援助,以促进他们的研究目标。这一实体汇集了NCI内许多不同的生物信息学专业知识,在广泛的生物信息学主题方面具有优势。CCBR目前正在为CCR内的80多名首席研究人员提供支持,并正在开展与几个不同一般领域有关的120个项目,包括对各种癌症基因组学领域的支持。最新的努力是在单细胞基因组学领域。自2011年成立以来,CCBR作为CCR生物信息学支持的“生态系统”发挥了越来越重要的作用。这一概念生态系统已经形成了科学协作以及计算、后勤和战略支持的关系。这一不断发展的模式使CCBR能够加强其对CCR实验室的核心服务,同时促进与CCR中其他服务设施和嵌入的生物信息学家的科学合作。各种科学和业务合作创建了一个虚拟保护伞,在该伞下,生物信息学支持集成到BACS/ABC业务的几个后勤部分。这些伙伴关系还充当了促进想法、解决方案和新机会的渠道。
英文摘要
The CCR Collaborative Bioinformatics Resource (CCBR) is an organizational umbrella which provides a mechanism for CCR researchers to obtain many different types of bioinformatics assistance to further their research goals. This entity pulls together many different bioinformatics expertise within NCI, with strengths in a broad range of bioinformatics topics. The CCBR currently is providing support to over 80 Principal Investigators within CCR and are working on 120 projects related to several different general areas, including support to a wide variety of cancer genomics areas. The newest efforts have been in the area of single-cell genomics. Since its inception in 2011, CCBR has played a progressively key role as an "ecosystem" for bioinformatics support in CCR. This conceptual ecosystem has formed relationships for scientific collaborations and for computational, logistical, and strategic support. This evolving model allows CCBR to strengthen its core service to CCR laboratories while fostering scientific collaborations with other service facilities and embedded bioinformaticians in CCR. The various scientific and operational collaborations create a virtual umbrella under which bioinformatics support is integrated across several logistical pieces of BACS/ABCS operations. These partnerships also act as a conduit for fostering ideas, solutions, and new opportunities.
期刊论文(32)
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会议论文
DOI: 10.1371/journal.pone.0094045
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者: [Baysan M, Woolard K, Bozdag S, Riddick G, Kotliarova S, Cam MC, Belova GI, Ahn S, Zhang W, Song H, Walling J, Stevenson H, Meltzer P, Fine HA]
通讯作者: Fine HA
DOI: 10.1056/nejmoa1502449
发表时间: 2015-07-30
期刊: The New England journal of medicine
影响因子: --
作者: [Gara SK, Jia L, Merino MJ, Agarwal SK, Zhang L, Cam M, Patel D, Kebebew E]
通讯作者: Kebebew E
DOI: 10.1016/j.celrep.2014.07.024
发表时间: 2014-08-21
期刊: Cell reports
影响因子: 8.8
作者: [Khurana S, Kruhlak MJ, Kim J, Tran AD, Liu J, Nyswaner K, Shi L, Jailwala P, Sung MH, Hakim O, Oberdoerffer P]
通讯作者: Oberdoerffer P
DOI: 10.1371/journal.pone.0096650
发表时间: 2014
期刊: PloS one
影响因子: 3.7
作者: [Ji Y, Abrams N, Zhu W, Salinas E, Yu Z, Palmer DC, Jailwala P, Franco Z, Roychoudhuri R, Stahlberg E, Gattinoni L, Restifo NP]
通讯作者: Restifo NP
共 20 条
    Biomarkers of Parkinson Disease and Related Disorders
    Treatment of Catecholamine-Related Disorders
    Biomarkers of Parkinson Disease and Related Disorders
    CCR Bioinformatics Core
    • 批准号:
      8763786
    • 项目类别:
    • 资助金额:
      $281.09万
    • 财政年份:
      --
    • 负责人:
      David Goldstein
    • 依托单位:
    海外基金