Novel tools for the imaging of tumor hypoxia using PET

快速生长的肿瘤通常会超出血管正常供应营养物质和氧气的能力。这会在肿瘤内形成缺氧的组织区域，并对放射和化疗具有高度抵抗力。使用核医学技术对这些区域进行成像现在已经成为癌症患者治疗计划的重要组成部分。该项目旨在改进现有药物的性能，以便更好地为特定类型的治疗选择患者。

Fast growing tumors often outgrow the ability of blood vessels to properly supply them with nutrients and oxygen. This creates tissue areas within the tumor that are lacking oxygen and are highly resistant to radiotherapy and chemotherapy. Imaging these areas using nuclear medicine techniques has now become important for therapy planning of cancer sufferers. This project aims to improve the properties of the existing agents in order to better select patients for a particular type of treatment.