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2009奥尔巴尼:第16次对话将于2009年6月16日至20日在纽约州立大学奥尔巴尼分校举行。晚上的主题演讲将由诺贝尔奖获得者斯坦福大学的Andrew Fire发表,主题是RNA干扰和与基因沉默相关的核酸结构。对话将涵盖结构生物学的以下领域:选择性剪接,无序蛋白质和胚胎干细胞;基因组学:系统生物学和网络;染色质与表观遗传学;RNA:基因组的沉默;RNA:核糖体及其对蛋白质合成的控制RNA:催化、折叠和相互作用RNA:结构信息学;重复:自私的DNA和有毒的RNA -人类疾病蛋白质- dna、DNA-DNA、蛋白质-蛋白质接触和基因调控;蛋白质:变构、网络通信和设计;细胞过程水平上的单分子可视化创新:合成生物学的瞬态结构Ned Seeman的DNA纳米技术会议;大分子复合物:低温电子显微镜和断层扫描。此外,会议结束后将立即举行一个关于核小体定位的卫星讲习班。这些主题将由特邀讲座和海报讨论文件涵盖。将有80场讲座,其中56场由资深科学家主持,24场由年轻科学家主持。青年研究人员(研究生,博士后研究员和起始教师)的演讲将基于提交的海报展示摘要的选择。在收到海报的摘要之前,将留出5.5小时的讨论会时间,以便从摘要中选择相当数量的讲座。海报数量将超过200张。在总共80场演讲中,女性科学家将至少发表30场演讲。该项目将招收来自20多个国家的约400名科学家。
英文摘要
DESCRIPTION (provided by applicant): Albany 2009: The 16th Conversation will be held in June 16-20 2009 at the State Univ. of New York at Albany. The Keynote evening lecture will be delivered by Nobel Laureate Andrew Fire, Stanford Univ. on RNA interference and nucleic acid structures associated with gene silencing. The Conversation will cover the following areas of structural biology: Alternative Splicing, Disordered Proteins and Embryonic Stem Cells; Genomics: System Biology and Networks; Chromatin and Epigenetics; RNA: Silencing of the Genome; RNA: Ribosome and Control of Protein Synthesis; RNA: Catalysis, Folding and Interactions; RNA: Structural Informatics; Repeats: Selfish DNA and Toxic RNA -Human Diseases; Protein-DNA, DNA-DNA, Protein- Protein Contacts and Gene Regulation; Proteins: Allostery, Network Communications and Design; Single Molecules Visualization at the Level of Cellular Processes; Innovation: Structure of Transients to Synthetic Biology; Ned Seeman's DNA Nanotechnology Session; Macromolecular complexes: cryo-electron microscopy & tomography. In addition a satellite workshop on Nucleosome Positioning will be held immediately following the Conversation. The subjects will be covered by invited lectures and poster discussion papers. There will be a total of 80 lectures, 56 by senior scientists and 24 by young researchers. Lectures by young researchers (graduate students, post-doctoral fellows and starting faculty) will be based on selection from abstracts submitted for poster presentation. 5.5 hours of the symposium time will be left vacant until abstracts for posters are received so that a significant number of lectures can be selected from the abstracts. The number of posters presented will be over 200. Out of a total of 80 talks, a minimum of 30 will be delivered by female scientists. The program will admit some 400 scientists from over 20 Nations. PUBLIC HEALTH RELEVANCE: Several of the sessions, such as Repeats: Selfish DNA and Toxic RNA -Human Diseases; Alternative Splicing, Disordered Proteins and Embryonic Stem Cells; Chromatin and Epigenetics; Protein-DNA, DNA-DNA, Protein-Protein Contacts and Gene Regulation; and Single Molecules Visualization at the Level of Cellular Processes deal directly with molecular diseases, and how one devises approaches to cure and manage them. The remaining topics look at advances in fundamental areas of medical biochemistry, and progress here will have profound impact on the way we will manage disease, including aging and cancer, in the future.
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