Albany 2011: The 17th Conversation

奥尔巴尼 2011：第 17 次对话

• 批准号: 8198459
• 负责人: RAMASWAMY H SARMA
• 金额: $ 0.7万
• 依托单位: STATE UNIVERSITY OF NEW YORK AT ALBANY
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-06-01 至 2012-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8198459
• 关键词: Aging; Area; Biochemistry; Biogenesis; Biological; Biology; Boston; Cell Nucleus; Chemistry; Chromosomes; Civilization; Country; DNA; DNA Repair; DNA-Protein Interaction; Development; Dimensions; Disabled Persons; Discipline; Disease; Elements; Event; Evolution; Faculty; Family; Female; Future; Genetic Transcription; Hereditary Disease; Hour; Housing; Individual; Knowledge; Laboratories; Left; Malignant Neoplasms; Medical; Minority; Molecular; Motion; Nanotechnology; Nerve Degeneration; New York; Paper; Persons; Physics; Planet Earth; Postdoctoral Fellow; Proteins; Recording of previous events; Research; Research Infrastructure; Research Personnel; Scientist; Senior Scientist; Staging; Structure; Students; System; Technology; Time; Universities; Woman; abstracting; base; frontier; graduate student; instrumentation; lectures; member; posters; prebiotic evolution; programs; simulation; social; structural biology; symposium

DESCRIPTION (provided by applicant): Albany 2011: The 17th Conversation will be held in June 14-18 2011 at the State Univ. of New York at Albany. The Keynote evening lecture will be delivered by Nobel Laureate Jack Szostak, Harvard, on the laboratory synthesis of self-replicating systems and the origin of life. The Conversation will cover the following areas of structural biology: Proteins: What is New, Newer and Newest? Proteins: Allostery, Cooperativity and Motion; Intrinsically Disordered Proteins and Neurodegeneration; Protein Evolution; Breakthroughs in Molecular Simulations; Evolution: Prebiotic Synthesis; Chromosomes - Landscape of the Cell Nucleus; Artificial DNA; DNA Nanotechnology; DNA-Protein Interactions; Cis-Regulatory Modules; DNA Damage and Repairs; Transcription-Replication Collisions. In addition there will be celebration of David Beveridge, a member of the Organizing Cmte since 1979. The subjects will be covered by invited lectures and poster discussion papers. There will be a total of 83 lectures, 55 by senior scientists and 28 by young researchers. Lectures by young researchers (graduate students, post-doctoral fellows and starting faculty) will be based on selection from abstracts submitted for poster presentation. 5.5 hours of the symposium time will be left vacant until abstracts for posters are received so that a significant number of lectures can be selected from the abstracts. The number of posters presented will be over 200. Out of a total of 83 talks, a minimum of 30 will be delivered by female scientists. The program will admit some 400 scientists from over 20 Nations. PUBLIC HEALTH RELEVANCE: Sessions such as Intrinsically Disordered Proteins and Neurodegeneration; DNA Damage and Repairs; Cis-Regulatory Modules; Chromosomes - Landscape of the Cell Nucleus; and DNA- Protein Interactions deal directly with molecular diseases, and how one devises approaches to cure and manage them. The remaining topics look at advances in fundamental areas of medical biochemistry, and progress here will have profound impact on the way we will manage disease, including aging and cancer, in the future.

描述(申请人提供)：奥尔巴尼2011：第17次对话将于2011年6月14-18日在州立大学举行。纽约的奥尔巴尼分校。晚上的主旨演讲将由哈佛大学诺贝尔奖得主杰克·绍斯塔克发表，主题是自我复制系统的实验室合成和生命的起源。对话将涵盖以下结构生物学领域：蛋白质：什么是新的、更新的和最新的？蛋白质：变构、协作性和运动；本质上无序的蛋白质和神经变性；蛋白质进化；分子模拟的突破；进化：益生合成；染色体-细胞核的景观；人造DNA；DNA纳米技术；DNA-蛋白质相互作用；顺式调节模块；DNA损伤和修复；转录-复制碰撞。此外，还将庆祝自1979年以来一直担任组委会成员的大卫·贝弗里奇。这些主题将通过特邀讲座和海报讨论论文来涵盖。共有83场讲座，其中55场由资深科学家主讲，28场由青年研究人员主讲。年轻研究人员(研究生、博士后研究员和初级教师)的演讲将基于从提交给海报演示的摘要中挑选出来的内容。5.5小时的专题讨论会时间将留出，直到收到海报摘要，以便可以从摘要中选择大量的讲座。展出的海报数量将超过200张。在总共83场演讲中，至少有30场将由女性科学家发表。该计划将接纳来自20多个国家的约400名科学家。 公共卫生相关性：会议，如固有的无序蛋白质和神经变性；DNA损伤和修复；顺式调节模块；染色体-细胞核的景观；DNA-蛋白质相互作用直接涉及分子疾病，以及如何设计治疗和管理这些疾病的方法。剩下的主题着眼于医学生物化学基本领域的进展，这里的进展将对我们未来管理疾病的方式产生深远影响，包括衰老和癌症。