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中文摘要
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摘要 对于典型的儿童来说,通过爬行来实现自主行动 行走是他们婴儿期的标志,并导致 认知、知觉和运动发育。对于患有显著疾病的儿童 行动能力障碍,如严重的脊柱裂、动力 轮椅提供了机动性和独立性,并可能导致 他们的发展是爆炸性的。目前,没有电力供应 轮椅和不适用于以下特殊需要婴儿的训练方案 2岁;因此,将电力机动性引入他们的生活的影响是 未知。 这项研究将首次量化集约权力的影响。 轮椅培训对任何诊断有特殊需要的婴儿。 具体地说,我们将量化训练对脊髓脊膜膨出婴儿的驾驶和发育的影响, 最常见也是最严重的一种脊柱裂。我们将对两组婴儿从7个月到12个月进行跟踪调查 几个月大的孩子。接受培训的婴儿将接受每周3次的标准化培训方案。婴儿将接受控制 在设备中的熟悉时间为每周1次。在整个研究过程中,将对训练组和对照组进行测试 他们的定向驾驶能力;他们在开放探索性驾驶中的驾驶长度、持续时间和路线;以及他们的 运动、知觉、认知和社会发展。 修订后的R21是正在进行的工程-婴儿康复的创新、可行的应用 合作,并将为第一个长期电力机动性的随机对照试验奠定基础 对有严重行动障碍的婴儿进行培训。
英文摘要
Abstract For the typical child, achieving independent mobility by crawling and walking is a hallmark of their infancy and results in an explosion of cognitive, perceptual and motor development. For children with significant mobility impairments, such as those with severe spina bifida, power wheelchairs provide mobility and independence, and potentially also lead to an explosion in their development. Currently, there are no power wheelchairs and no training protocols for special needs infants less than 2 yrs of age; thus the effect of introducing power mobility into their lives is unknown. This study will be the first to quantify the effect of intensive power wheelchair training on special needs infants with any diagnosis. Specifically, we will quantify the effect of training on the driving and development of infants with myelomeningocele, the most common, yet most severe form of spina bifida. We will follow two groups of infants from 7 months to 12 months of age. Training infants will receive a standardized training protocol 3x/week. Control infants will receive time in the device for familiarization 1x/week. Both training and control groups will be tested throughout the study on their directional driving ability; their driving length, duration and path during open exploratory driving; and their motor, perceptual, cognitive and social development. This revised R21 is an innovative, feasible application of ongoing engineering-infant rehabilitation collaboration, and will provide the foundation for the first randomized controlled trial of long term power mobility training of infants with significant mobility impairments.
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ADVANCING LOCOMOTION AND DEVELOPMENT IN YOUNG CHILDREN WITH DOWN SYNDROME
  • 批准号:
    8622489
  • 项目类别:
  • 资助金额:
    $22.19万
  • 财政年份:
    2014
  • 负责人:
    JAMES C. GALLOWAY
  • 依托单位:
MOTOR LEARNING AND COORDINATION IN HIGH RISK INFANTS
  • 批准号:
    8049429
  • 项目类别:
  • 资助金额:
    $0.84万
  • 财政年份:
    2010
  • 负责人:
    JAMES C. GALLOWAY
  • 依托单位:
ROBOT-ASSISTED MOBILITY FOR INFANTS WITH SEVERE SPINA SPINA
  • 批准号:
    8090079
  • 项目类别:
  • 资助金额:
    $0.62万
  • 财政年份:
    2010
  • 负责人:
    JAMES C. GALLOWAY
  • 依托单位:
MOTOR LEARNING AND COORDINATION IN HIGH RISK INFANTS
  • 批准号:
    7844168
  • 项目类别:
  • 资助金额:
    $0.84万
  • 财政年份:
    2009
  • 负责人:
    JAMES C. GALLOWAY
  • 依托单位:
国内基金
海外基金
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
  • 批准号:
    JCZRQN202500010
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
  • 依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
  • 批准号:
    2025JJ70209
  • 项目类别:
    省市级项目
  • 资助金额:
    --
  • 批准年份:
    2025
  • 负责人:
    雷芬芳
  • 依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
  • 批准号:
    --
  • 项目类别:
    面上项目
  • 资助金额:
    --
  • 批准年份:
    2024
  • 负责人:
    万荣
  • 依托单位: