Research Training in Anesthesia

描述（由申请人提供）：麻醉的实践正在迅速扩展到手术室之外。除了临床和基础科学研究之外，麻醉师越来越多地在重症监护、疼痛管理、对住院紧急情况的快速反应方面发挥作用。快速变化的医疗环境要求下一代麻醉领导者在临床和基础科学和转化科学方面接受广泛的培训。本博士后培养计划的目标是为青年科学家提供基础和转化研究领域的杰出经验。该计划的主要重点将是培养下一代医师学者（那些拥有医学博士或医学博士/博士学位的人）。该项目每年将资助2名研究员，为期2年，即每年有4个资助名额。我们为研究培训设想了四条轨道，每一条都将利用耶鲁大学麻醉系以及医学中心和大学其他项目的杰出专业知识。血管生物学课程将结合耶鲁大学成熟的跨学科血管生物学和治疗学（VBT）项目，利用麻醉领域的培训师。炎症/免疫生物学课程将包括来自免疫生物学系和人类转化免疫学的培训师，这两个部门都包括世界级的研究人员。生物工程方向将包括来自麻醉、生物工程系和诊断成像领域的杰出团队的研究人员。第四个轨道，临床研究，也将利用部门内部的培训资源，以及最近在耶鲁大学获得的CTSA项目。为了进一步推进医师科学家的培训，并且独立于T32申请，我们最近建立了一个住院学者计划（RSP）。RSP完全由麻醉科资助，并在3年的麻醉住院医师期间提供密集的研究指导。我们预计，这些在RSP中被高度选中的居民在完成他们的住院医师后，将成为这个T32博士后培训计划的优秀候选人。

DESCRIPTION (provided by applicant): The practice of Anesthesia is rapidly expanding beyond the boundaries of the operating room. Increasingly, anesthesiologists are taking a roles is critical care, the management of pain, rapid response to inpatient emergencies, in addition to clinical and basic science research. Rapidly changing healthcare environments require that the next generation of leaders in anesthesia be broadly trained, both clinically and in basic and translational science. The goals of this post-doctoral training program are to provide young scientists with outstanding experiences in basic and translational research arenas. The primary focus of the program will be to train the next generation of physician scholars (those having MD or MD/PhD degrees). This program will fund 2 fellows per year for 2 years, meaning 4 funded slots per year. We envision four tracks for research training, each of which will draw on outstanding expertise at Yale, both within the Department of Anesthesia, and in other programs in the Medical Center and the University. The Vascular Biology track will leverage trainers within Anesthesia, in conjunction with the well-established and interdisciplinary Vascular Biology and Therapeutics (VBT) program at Yale. The Biology of Inflammation/Immunity track will involve trainers from the Department of Immunobiology and from the Human Translational Immunology, both of which include world-class investigators. The Bioengineering track will include investigators from Anesthesia, as well as the Bioengineering Department and outstanding groups in Diagnostic Imaging. The fourth track, Clinical Research, will also leverage training resources within the Department, as well as the recently-awarded CTSA program at Yale. To further advance the training of physician scientists, and independent of this T32 application, we have recently established a Resident Scholars Program (RSP). The RSP is funded entirely by the Anesthesia department, and provides intensive mentoring in research during the 3 years of anesthesia residency. We anticipate that many of these highly select residents in the RSP will be excellent candidates for enrollment in this T32 postdoctoral training program upon completion of their residency. Relevance: This grant will fund advanced research training for clinical anesthesiologists, in both basic science and in clinically oriented research. By providing outstanding training to practicing physicians, we are improving the delivery and advancement of healthcare nationwide, because these trained physicians will drive the development of new therapies and improved ways of caring for patients.