Research in Perinatal Medicine

项目简介：自1977年成立以来，该博士后项目的目标是为新生儿学家和其他对发育医学感兴趣的人提供成功学术生涯所需的技能。尽管在美国有许多新生儿-围产期医学的临床培训项目，但很少提供在发育生物学方面的强化实验室经验，或在临床研究和流行病学方面的结构化培训。耶鲁大学的临床和基础科学系都参与了该项目，包括儿科、内科、遗传学、病理学、细胞和分子生理学、神经生物学、免疫生物学和流行病学。受训者可以利用这些部门的广泛资源，以及新生特别护理科的设施，这是耶鲁-纽黑文儿童医院的一个51张床位的三级护理科。对于选择强化实验室研究经验的学员，可以在细胞生物学，分子生物学和遗传学方面进行结构化课程。选择临床研究的学员要参加临床试验设计、统计学和流行病学等课程。他们也可能成为耶鲁大学公共卫生学院公共卫生硕士学位或调查医学博士学位的候选人。本项目培养博士后4人。受训者被任命为3年，必须致力于追求学术医学的职业生涯。医学博士学员将在进入项目前完成实习。博士毕业生将对发育生物学有明显的兴趣。经过一段时间的培训，受训者选择一个导师和一个研究项目。在导师的直接监督下，他们设计、执行、解释和报告他们的研究。由于三年通常不足以建立独立的研究生涯，因此鼓励和协助受训者申请资助以延长他们的研究训练，许多人已经成功地这样做了。这个项目的毕业生在美国各地担任学术职位，目前已经运作了28年以上。许多人已经成为围产期医学和研究的领导者。相关性：医师科学家为生物医学研究及其翻译带来了独特的视角。人们已经认识到，全国缺乏受过适当训练的内科科学家。该方案的持续目标是培养下一代围产期调查员的成员。

DESCRIPTION (provided by applicant): Project Summary: The goal of this postdoctoral program, since its inception in 1977, has been to provide neonatologists and others interested in developmental medicine with the skills necessary for a successful academic career. Although there are many clinical training programs in neonatal-perinatal medicine in the United States, few offer either an intensive laboratory experience in developmental biology, or structured training in clinical research and epidemiology. Both clinical and basic science departments at Yale University are involved with the program including Pediatrics, Internal Medicine, Genetics, Pathology, Cellular and Molecular Physiology, Neurobiology, Immunobiology and Epidemiology. The extensive resources of these departments are available to trainees as are the facilities of the Newborn Special Care Unit, a 51 bed tertiary care unit in the Yale-New Haven Children's Hospital. For the trainees who choose an intensive laboratory based research experience, structured course work is available in cell biology, molecular biology and genetics. Trainees who elect to do clinical research attend courses in design of clinical trials, statistics and epidemiology. They may also become candidates for the MPH degree at the Yale School of Public Health or the PhD in Investigative Medicine. This program supports 4 postdoctoral trainees. Trainees are appointed for 3 years and must be committed to pursuing a career in academic medicine. MD trainees will have completed their residency prior to entering the program. PhD graduates will have a demonstrated interest in developmental biology. After an orientation period, trainees select a preceptor and a research project. Under the direct supervision of the preceptor, they design, execute, interpret and report their research. Since 3 years are generally insufficient to establish an independent research career, trainees are encouraged and assisted to apply for funding to extend their research training, and many have done so successfully. Graduates of this program, which has now been functioning for over 28 years, hold academic positions throughout the United States. Many have become leaders in perinatal medicine and research. Relevance: Physician-scientists bring a unique perspective to biomedical research and its translation. It has been recognized that there is a national shortage of suitably trained physician-scientists. The ongoing objective of this program is to train members of the next generation of perinatal investigators.