Pilot and Feasibility Program

在过去的10年里。试行可行性项目申请已按年征集 由耶鲁大学医学院广泛向全体教职员工“征集申请”。自1999年以来，这 公告已包括在该中心的网站上，并通过电子邮件分发给所有医学院 和基础科学教员。 试点赠款的主要目的是获得数据，以便申请未来的R01资金。 申请资助的对象依次为：1)高级博士后研究员和无肝初级教员 相关研究支持2)其他领域的知名研究人员和3)正在变化的中心成员 他们的研究方向。现有中心成员只有在申请支持以下项目时才有资格获得试点资金 对新离职人员的资助以前没有得到支持，也没有被解释为对其现有研究基础的延续。 申请者不得获得超过一个项目的资助，并且在给定的5年补助金中获得不超过1-2年的资助 句号。在过去5年中，只有3名调查人员获得了第二年的试点资金，预算为 在第二年减少了其中的两个。向被任命的新调查员提供了三年的资金 (Iwakiri)每中心指南。因此，绝大多数试点只获得了一年的资金。 申请拨款的日期为每年12月至1月；递交意向书的意向书 2月1日前将试点可行性资金申请提交给中心管理人员和主任 然后，执行委员会确定申请人是否有资格获得试点资金。申请被拒绝 如果他们不符合上述标准或不专注于中心的使命。应用程序来自 批准的申请者在3月份收到，遵循严格的页数限制和使用PHS 398补助金的指导方针 格式化。这些指南分发给所有申请试点资金的申请者，并张贴在该中心的网站上。 执行委员会对申请进行简要审查，以确保合规性，并将其分配给两个主要 评审员主要在大学内部，但根据专业知识的要求在机构外进行审查。在收到 审查，执行委员会批准或拒绝申请，决定函由 中心主任向每一位申请者发送经过编辑的评论。如果建议获得批准，则会将其退还给申请人 用于建议的改进和预算更改。最终修订后的申请将于5月初收到。所有的 然后，将这些申请连同小学和小学的作业一起转发给外部咨询委员会 二次评审员。外部咨询委员会随后于晚些时候在该中心作为研究科举行会议。 五月或六月初。听取试点申请者的陈述，并独立投票批准或 不同意，并确定优先分数和建议预算。然后，这一过程决定了 从9月1日开始的下一财年的试点可行性计划。然后是中心主任 在给申请者的一封信中传达这些发现。此过程的唯一例外是 由于申请截止日期的时间限制，外部咨询委员会审查 试点通过电子邮件申请，并在需要时召开电话会议，以分配资金的最终优先事项。 对已完成的试点项目或第二年资金申请的年度报告也进行了审查 在外部咨询委员会会议时。第二年的资助不是自动的，只有在以下情况下才会获得批准 在该奖项的第一年期间，只有在相对科学价值大于 目前正在审查的其他相互竞争的项目。 除了在年度外部咨询委员会会议上的陈述外，飞行员获奖者通常 作为中心丰富方案的一部分，参加每周系列研讨会和一年两次的中心 撤退。如果调查员离开机构或以其他方式没有执行原始的 项目的意图。申请下一年度的结转资金必须得到行政部门的批准 委员会，只有在特殊情况下才允许。

During the past 10 years. Pilot Feasibility Project Applications have been solicited on an annual basis by a Yale University School of Medicine wide "call for applications" to all faculty members. Since 1999, this announcement has been included on the Center's website as well as distributed by e-mail to all medical school and basic science faculty. The primary purpose of the pilot grants is to obtain data to enable applications for future R01 funding. Candidates for funding in order of priority consist of: 1) Senior post-doctoral fellows and junior faculty without liver related research support 2) Established investigators in other fields and 3) Center members who are changing directions of their research. Existing Center members are eligible for pilot funding only if they request support for funding of new departures not previously supported or construed as a continuation of their present research base. No applicant receives funding for more than one project and no more than 1-2 years in a given 5-year grant award period. Only 3 investigators received a 2nd year of pilot funding during the past 5 years, and budgets were reduced for 2 of them in the second year. Three years of funding was provided to the Named New Investigator (Iwakiri) per Center guidelines. Thus, the vast majority of the pilots were funded for only one year. The call for applications for funding is made in Dec-Jan of each year; Letters of intent to submit an application for pilot-feasibility funding are submitted to the Center Administrators by February 1st and the Director and Executive Committee then establish whether the applicant is eligible for pilot funding. Applications are denied if they do not fill the above-mentioned criteria or are not focused on the Center's mission. Applications from approved applicants are received in March following strict guidelines for page limits and using a PHS 398 grant format. These guidelines are distributed to all applicants for pilot funding and are posted on the Center's web site. The applications are reviewed briefly for compliance by the Executive committee and assigned to two primary reviewers primarily inside the University but outside the institution as expertise demands. Following receipt of the reviews, the Executive Committee either approves or rejects the applications and letters of decision are sent by the Center Director to each applicant with edited reviews. If the proposal is approved, it is returned to the applicant for suggested improvements and budget alterations. A final revised application is received by early May. All of these applications are then forwarded to the External Advisory Board together with assignments of primary and secondary reviewers. The External Advisory Board subsequently meets at the Center as a study section in late May or early June. Presentations are heard from the pilot applicants and independently votes approval or disapproval and establishes a priority score and suggested budget. This process then determines the funding of the Pilot Feasibility Program for the next fiscal year that begins September 1st. The Center Director then communicates these findings in a letter to the applicants. The only exception to this procedure is the year of the competitive renewal when, due to time constraints to the application deadline, the External Advisory Board reviews the pilot applications via email and holds a conference call if needed to assign final priorities for funding. Annual reports for completed pilot projects or applications for a second year of funding are also reviewed at the time of the External Advisory Board Meeting. A 2nd year of funding is not automatic and is approved only if there is significant progress during the first year of the award and only if the relative scientific merit is greater than other competing projects which are under current review. In addition to their presentations at the annual External Advisory Board meeting, Pilots recipients often participate as part of the Center's Enrichment Program in the weekly seminar series and the biannual Center retreats. Pilots are terminated if the investigator leaves the institution or otherwise does not carry out the original intent of the project. Requests for carryover funding to the next year must be approved by the Executive Committee and are allowed only in exceptional circumstances.