Exceptional Survival in Danish and Italian Families

描述（由申请人提供）：丹麦和意大利家庭的特殊生存 我们建议在NIA RFA中要求对“家庭中的特殊生存”（ESF）进行研究。在 特别地，我们计划收集1000对（一半在丹麦，一半在意大利）在世的90岁和100岁同胞及其在世的兄弟姐妹篇和子女的问卷调查和生理数据。我们还将收集同胞父母的寿命信息。我们将通过检查出生证，并在适当时检查结婚证和死亡证来核实年龄。我们将与其他ESF学习中心合作，制定适当的问卷和调查程序。我们将与其他ESF研究中心合作，开发强大、适当的统计/人口分析模型和方法，以研究数据。

DESCRIPTION (provided by applicant): Exceptional Survival in Danish and Italian Families We propose research requested in the NIA RFA on "Exceptional Survival in Families" (ESF). In particular, we plan to gather questionnaire and physiological data on 1000 pairs (half in Denmark and half in Italy) of living nonagenarian and centenariala sibs and their living brothers, sisters and children. We will also gather information on the lifespans of the sibs' parents. We will validate ages by examining birth certificates and, when appropriate, marriage certificates and death certificates. We will collaborate with other ESF Study Centers to develop appropriate questionnaires and survey procedures. We will develop powerful, appropriate models and methods of statistical/demographic analysis to study the data in collaboration with other ESF Study Centers.