Jules Stein Eye Institute Core Grant for Vision Research

描述(由申请人提供)：加州大学洛杉矶分校朱尔斯·斯坦眼科研究所(JSEI)及其附属部门的视觉研究部由15名由NEI资助的视觉科学家组成。JSEI视觉研究核心助学金的目标是提供急需的基础设施，以支持这群有才华的科学家的研究活动，他们的共同目标是增加视觉系统及其疾病的基本知识。为实现这一目标，人员和仪器支持设施的组织如下 模块：(1)生物化学和分子生物学仪器；(2)显微镜和成像；(3)机器车间；(4)实时成像和功能评估。这些模块提供多个实验室共同使用的仪器，对于正在进行的项目的成功以及实现新的合作努力是必不可少的。由于联合经济倡议通过各种捐助者的慷慨捐助以及最近从《美国复苏和再投资法》获得的资金，能够购买模块中最先进的工具。要求以核心赠款的形式提供支助，以便通过仪器服务合同维护这些模块，并提供必要的人员支助，以协助和培训用户并提供日常维护。

DESCRIPTION (provided by applicant): The Vision Research Division of the Jules Stein Eye Institute (JSEI) and affiliated Departments at UCLA consists of 15 vision scientists with NEI funding. The objective of the Core Grant for Vision Research at the JSEI is to provide a critically needed infrastructure to support the research activities of this talented group of scientists whose common goal is to increase basic knowledge of the visual system and its disorders. To achieve this objective, personnel and instrument support facilities are organized according to the following modules: (1) Biochemistry and Molecular Biology Instrumentation; (2) Microscopy and Imaging; (3) Machine Shop and (4) Live imaging and Functional Evaluation. These Modules provide instrumentation commonly used by multiple laboratories and are essential to the success of on-going projects as well as to enable new collaborative efforts. Purchase of state-of-the-art instruments in the modules was made possible by the generosity of the JSEI through various donors as well as recent funds from the American Recovery and Reinvestment Act. Support in the form of the Core grant is requested to maintain these Modules through instrument service contracts, and to provide necessary personnel support to assist and train users and provide routine maintenance.