PS09-007, Evaluating Locally-Developed Homegrown HIV Prevention Interventions

描述（由申请人提供）：美国东南部拥有该国增长最快的拉丁裔人口，同时承担着不成比例的艾滋病毒负担。 对拉丁美洲人或男男性行为者（MSM）几乎没有有效的艾滋病毒预防干预措施。 为响应RFA-PS-09-007“评估非裔美国人和西班牙裔/拉丁裔男男性行为者当地开发（本土）的艾滋病毒预防干预措施”，我们的社区-大学合作伙伴关系提出了一项为期5年的研究（U 01），以加强、全面实施和严格评估一项旨在增加拉丁裔男男性行为者安全套使用和艾滋病毒检测的小组干预措施。 干预措施是由查塔姆社会卫生理事会工作人员和社区合作伙伴，包括拉丁美洲男男性接触者，并根据社会认知理论和赋权教育理论。 这项拟议的研究是社区与大学长期合作的结果。 总共将招募300名拉丁裔MSM。参与者将完成一项初步的基线风险行为评估，旨在衡量当前的性行为，以及心理，社会和文化对性行为和医疗保健使用的影响。 然后，参与者将被随机分配到4个会议的小组艾滋病毒预防干预（HOLA en Grupos）或4个会议的小组癌症预防教育比较干预。 所有参与者还将在3个月和12个月随访时完成相同的评估。 与对照组中的同龄人相比，HIV预防干预的参与者预计将表现出（a）在性交期间增加自我报告的避孕套使用;（B）增加自我报告的HIV和性传播疾病（STD）咨询、检测和治疗服务的使用;（c）更多地了解艾滋病毒对社区的影响（包括拉丁美洲人和男男性行为者），以及艾滋病毒风险行为和预防战略;（d）对禁欲和使用避孕套采取更积极的态度;（e）增加使用和坚持使用避孕套的自我效能;（f）增加掌握感得分;（g）减少减少风险的障碍（例如，大男子主义有损健康的方面）;以及（h）加强伙伴和提供者的沟通和性谈判技能。 这项研究的结果和产品将被传播，以告知公共卫生实践，研究和政策。 成果和产品将包括：（1）西班牙语干预措施：具有文化相关性;旨在降低拉丁美洲男男性行为者的艾滋病毒风险，并准备传播;（2）更深入地了解拉丁美洲男男性行为者的艾滋病毒风险和干预措施。 公共卫生相关性：对于拉丁美洲人或男男性行为者（MSM），几乎没有有效的艾滋病毒预防干预措施。 我们建议加强，全面实施，并严格评估当地开发的干预措施的有效性，旨在减少拉丁美洲男男性行为者在美国所承担的不成比例的艾滋病毒负担。

DESCRIPTION (provided by applicant): The Southeastern United States has the fastest-growing Latino population in the country and at the same time carries a disproportionate HIV burden. Few efficacious HIV prevention interventions exist for either Latinos or men who have sex with men (MSM). In response to RFA-PS-09-007 "Evaluating Locally-Developed (Homegrown) HIV Prevention Interventions for African American and Hispanic/Latino MSM," our community-university partnership proposes a 5-year study (U01) to enhance, fully implement, and rigorously evaluate a small-group intervention designed to increase condom use and HIV testing among Latino MSM. The intervention was developed by Chatham Social Health Council staff and community partners, including Latino MSM, and is based on social cognitive theory and theory of empowerment education. The proposed study is a result of a long-term community-university partnership. A total of 300 Latino MSM will be enrolled. Participants will complete an initial baseline risk behavior assessment designed to measure current sexual behavior, and psychological, social, and cultural influences on sexual behavior and healthcare use. Participants then will be randomized to a 4-session small-group HIV prevention intervention (HOLA en Grupos) or a 4-session small-group cancer prevention education comparison intervention. All participants also will complete identical assessments at 3-month and 12-month follow-up. Participants in the HIV prevention intervention, relative to their peers in the comparison group, are anticipated to demonstrate (a) increased self-reported use of condoms during sexual intercourse; (b) increased self-reported use of HIV and sexually transmitted disease (STD) counseling, testing, and treatment services; (c) greater knowledge of the impact of HIV on communities (including Latino and MSM), and HIV risk behaviors and prevention strategies; (d) more positive attitudes towards abstinence and condom use; (e) increased self- efficacy to use and assert the use of condoms; (f) increased sense of mastery scores; (g) decreased barriers to risk reduction (e.g., health-compromising aspects of machismo); and (h) enhanced partner and provider communication and sexual negotiation skills. The results and products from this study will be disseminated to inform public health practice, research, and policy. Results and products will include: (1) a Spanish-language intervention that is: culturally relevant; designed to reduce HIV risk among Latino MSM, and ready for dissemination; and (2) a deeper understanding of HIV risk and intervention among Latino MSM. PUBLIC HEALTH RELEVANCE: Few effective HIV prevention interventions exist for either Latinos or men who have sex with men (MSM). We propose to enhance, fully implement, and rigorously evaluate the effectiveness of a locally developed intervention designed to reduce the disproportionate HIV burden borne by Latino MSM in the United States.