ADVANCES IN OPTICS FOR BIOTECHNOLOGY, MEDICINE AND SURGERY CONFERENCE XII

描述（由申请人提供）：本提案请求资金支持“生物技术、医学和外科光学进展”，这是一个专注于生物医学光学领域的小型跨学科会议。生物医学光学是指在医学和生物医学研究中使用光，并利用从紫外线到红外线波长的组织与光之间可能发生的许多相互作用。这一年轻领域所包含的广泛技术对医学诊断和治疗以及生物医学研究产生了深远的影响。通过利用血液中氧和脱氧血红蛋白的吸收特性，光学成像可用于评估组织功能和灌注。水吸收光是激光手术的基础。固有荧光团包括一系列代谢物，可以用来描述体内的恶性病变。越来越多的光学造影剂被开发出来，并辅以新的转基因技术，可以特异性地指导单个细胞类型产生荧光造影剂。光学成像技术的发展，使得从整个头部或乳房到单个细胞或亚细胞组件的许多对比机制在长度尺度上的可视化或利用，涵盖了包括物理、工程、数学和计算在内的广泛学科。因此，这个高度跨学科的领域需要广泛的技能，将这些技术领域与对医学、生物医学和生物化学目标和应用的深刻理解相结合。本次会议将汇集来自生物医学光学研究各个方面的专家，包括临床医生和行业专家。会议形式旨在促进医学和工程广泛领域的创意分享，同时为学生和学员提供丰富的机会，使他们的知识多样化，并与该领域的主要领导者建立关系。会议将于2011年6月5日至8日在美国佛罗里达州那不勒斯的那不勒斯海滩酒店举行，会议将由有成就的高级或新兴专家的邀请演讲组成。海报会议将为学生和博士后提供充分的机会来描述和讨论他们的工作。美国国立卫生研究院提供的资金将用于支付学生和受邀演讲者的注册和旅行费用。因此，本次会议的目的是：目标1：确定生物医学光学领域最新和最尖端的发展，并提供一个分享这些新发现和想法的论坛。目标2：纳入对该领域具有根本重要性的主题，以促进跨学科的学习和培训，并确定有希望的模式在更广泛采用/商业化方面取得的进展。目标3：确保演讲者和与会者的多样性，确保所有有能力为会议做出贡献并从中获益的人都有机会参加会议并展示他们的工作。目标4：创造一个促进交流、思想交流、合作和跨学科学习的环境。

DESCRIPTION (provided by applicant): This proposal is requesting funds to support "Advances in Optics for Biotechnology, Medicine and Surgery", a small, interdisciplinary conference focused on the field of biomedical optics. Biomedical optics refers to the use of light in medicine and biomedical research, and exploits the many interactions that can occur between tissue and light from ultra-violet to infra-red wavelengths. The broad range of techniques encompassed by this young field are having profound impacts on medical diagnostics and therapy, as well as in biomedical research. By harnessing the absorption properties of oxy- and deoxy-hemoglobin in blood, optical imaging can be used to evaluate tissue function and perfusion. Absorption of light by water is the basis of laser surgery. Intrinsic fluorophores include a range of metabolites and can be exploited to delineate malignant lesions in- vivo. A wide range of optical contrast agents are increasingly being developed, and are complemented by new transgenic techniques that can specifically instruct individual cell types to generate fluorescence contrast. Development of optical imaging techniques that can allow visualization or exploitation of these many contrast mechanisms over length-scales from the whole head or breast, to single cells or sub-cellular components encompasses a wide range of disciplines including physics, engineering, mathematics and computing. This highly interdisciplinary field therefore requires broad skills sets that combine these technical areas with a deep understanding of medical, biomedical and biochemical targets and applications. This meeting will draw together experts from all facets of biomedical optics research, including clinicians and experts from industry. The conference format is designed to stimulate the sharing of creative ideas across broad areas of medicine and engineering, while providing ample opportunities for students and trainees to diversify their knowledge and develop relationships with key leaders in the field. The conference will be held from the 5-8th June 2011 at Naples Beach Hotel, Naples, Florida, USA and sessions will be composed of invited talks from accomplished senior or rising experts. A poster session will provide students and post- doctoral fellows with ample opportunities to describe and discuss their work. Funds provided by the NIH will be used to defray registration and travel costs for students and invited speakers. The aims of this meeting are therefore: Aim 1: To identify the newest and most cutting edge developments in the field of biomedical optics, and provide a forum for sharing these new discoveries and ideas. Aim 2: To incorporate topics of fundamental importance to the field to facilitate interdisciplinary learning and training, and to ascertain the progress of promising modalities towards wider adoption / commercialization. Aim 3: To ensure diversity in both speakers and attendees, ensuring that all who have the capacity to contribute to, and gain from the meeting are afforded the opportunity to attend and showcase their work. Aim 4: To create an environment that stimulates networking, exchange of ideas, collaboration, and cross-disciplinary learning. PUBLIC HEALTH RELEVANCE: Project Narrative "Advances in Optics for Biotechnology, Medicine and Surgery" is a small (~120 attendee), interdisciplinary conference focused on the field of biomedical optics, which encompasses the use of light for a wide range of imaging, diagnostic and therapeutic applications in medicine and biomedical science. This conference will bring together established experts in all areas of this field, along with students, clinicians and representatives from industry. The meeting will focus on novel and emerging technologies as well as fundamental concepts, and will encourage networking and idea exchange between its diverse participants.