AANCART: The National Center for Reducing Asian American Cancer Health Disparitie

描述(由申请人提供)：为响应RFA-CA-09-032，亚裔美国人癌症意识、研究和培训网络(AANCART)建议创建名为AANCART的国家减少亚裔美国人癌症健康差距中心：国家中心。该中心由学术和社区首席调查人员领导，将使用以社区为基础的参与性研究(CBPR)方法来实现其具体目标：1)建立一个国家中心，以AANCART在过去9年中创建的社区-学术伙伴关系网络为基础进行外展、研究和培训，作为NCI资助的社区网络计划，该计划已经产生了许多重大成就，并在社区中建立了信任；2)扩展到社区，以减少亚裔美国人中的癌症差异和相关的共同疾病；3)开展、培育和传播循证干预研究，以减少亚裔美国人面临的不必要的癌症负担；4)培训和培养新的和早期的CBPR调查人员，以提交同行审查的建议并获得资金，以开展研究以减少健康差距。此U54应用程序显示：1)中心是如何管理组织的；2) 如何在加利福尼亚州和夏威夷的4个亚裔美国人群体中实施外联计划，创建和增加获得文化上合适的、语言上特定的和以证据为基础的材料，旨在增加关于癌症的知识和使用有益的预防程序；3)为期5年的全面研究项目将如何制定、实施、评估和传播非专业健康教育人员在4个地区(火奴鲁鲁、洛杉矶、萨克拉门托和旧金山)的4个亚裔美国人群体(菲律宾人、苗族人、韩国人和越南人)中促进结直肠癌筛查的随机对照整群试验的结果，以及为期2年的先导研究项目将如何评估华裔美国人对生物标本收集的认知和文化视角；以及4)培训计划如何通过结合个性化的指导计划、预定的研讨会和与NIH临床和翻译科学奖相关的课程来培养新的和早期的研究人员。

DESCRIPTION (provided by applicant): In response to RFA-CA-09-032, the Asian American Network for Cancer Awareness, Research, and Training (AANCART) proposes to create the National Center for Reducing Asian American Cancer Health Disparities entitled AANCART: The National Center. This Center, led by academic and community Principal investigators, will use a community-based participatory research (CBPR) approach to achieve its Specific Aims: 1) Build a National Center to conduct outreach, research, and training based on the network of community-academic partnerships created by AANCART in the preceding 9 years as an NCI-funded Community Network Program, which has generated many significant accomplishments and established trust in the community; 2) Outreach to communities to reduce cancer disparities and related co-morbid conditions among Asian Americans; 3) Conduct, foster, and disseminate evidence-based intervention Research to reduce the unnecessary cancer burden confronting Asian Americans; 4) Train and nurture new and early stage CBPR investigators to submit peer-reviewed proposals and obtain funding to conduct research to reduce health disparities. This U54 application shows: 1) How the Center is administratively organized; 2) How the Outreach Program will be implemented among 4 Asian American populations in California and Hawaii by creating and increasing access to culturally appropriate, linguistically-specific, and evidence-based materials designed to increase knowledge about cancer and the use of beneficial preventive procedures; 3) How a 5-year Full Research Project will develop, implement, evaluate, and disseminate the results of a cluster randomized controlled trial of the efficacy of lay health educators to promote colorectal cancer screening among 4 Asian American groups (Filipinos, Hmong, Korean, and Vietnamese) in 4 regions (Honolulu, Los Angeles, Sacramento, & San Francisco) and how a 2-year Pilot Research Project will assess cognitive & cultural perspectives among Chinese Americans regarding biospecimen collection; and 4) How a Training Program will develop new and early stage investigators by combining individualized mentoring plans, scheduled seminars, and a curriculum linked to the NIH Clinical & Translational Science Awards.