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中文摘要
翻译
生物银行在癌症研究中的作用。越来越多的健康研究人员和行业正在认识到生物银行的价值及其与医疗记录数据、表型信息和社会人口数据的联系(93)。生物库是遗传和公共卫生研究的重要资源,包括研究基因型之间的关联、环境暴露的措施以及了解疾病的作用
英文摘要
Role of Biobanks in Cancer Research. Increasingly, health researchers and industry are realizing the value of biobanks and their linkages to medical record data, phenotypic information, and sociodemographic data (93). Biobanks serve as essential resources for genetic and public health research, including studies of associations between genotypes, measures of environmental exposures, and understanding the role of genetics in disease susceptibility (92). Biobanks generally collect specimens from two distinct groups: (1) the general public and (2) disease-specific populations. The primary goal of the general population biobank is to identify biomarkers and genetic markers for disease susceptibility among a large, representative population of healthy people. The disease-orientated biobanks focus on identifying biomarkers of exposure and tjiomarkers of disease, such as colorectal cancer (94). Some biobanks target sub-populations like women or geographical regions (92). Biobanks of varying size are found all over the world and they are often funded by government entities (91).
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Research Project
  • 批准号:
    8538095
  • 项目类别:
  • 资助金额:
    $5.0万
  • 财政年份:
    2012
  • 负责人:
    Jean Guillaume Ford
  • 依托单位:
Community Networks Program: The Johns Hopkins Center to Reduce Cancer Disparities
  • 批准号:
    8009594
  • 项目类别:
  • 资助金额:
    $81.16万
  • 财政年份:
    2010
  • 负责人:
    Jean Guillaume Ford
  • 依托单位:
Community Networks Program: The Johns Hopkins Center to Reduce Cancer Disparities
  • 批准号:
    8137964
  • 项目类别:
  • 资助金额:
    $81.96万
  • 财政年份:
    2010
  • 负责人:
    Jean Guillaume Ford
  • 依托单位:
Training Program
  • 批准号:
    8033497
  • 项目类别:
  • 资助金额:
    $2.23万
  • 财政年份:
    2010
  • 负责人:
    Jean Guillaume Ford
  • 依托单位:
海外基金