NEI Mentored Clincial Scientist Development Program Award (K12)

描述(由申请人提供)：这是一份机构培训拨款提案，旨在培养下一代临床医生-科学家在眼科的学术职位。38年来，杜克大学眼科中心(DUEC)在培养学术眼科医生方面一直处于全国领先地位。这些学员中最早的几代人现在在国内外学术医学中心的许多领导职位上任职。他们担任院长、系主任和教职员工，并担任院士的导师。我们建议通过一个密集的计划来延续这一传统，旨在提供必要的指导、资源和授课教学，以培养眼科学术职位的临床医生-科学家。我们计划每年挑选两名完成眼科或病理学实习的学员，为期3年。 教育计划将导致独立的同行评议的拨款和教员职位 在一所学术机构工作。受训人员将接受密集的教学课程，并结合 杜克大学资深教师的密切指导。每名学员都将接受强制性培训 临床研究、遗传学、统计学、科学写作、拨款准备、伦理学和 负责任的研究行为。每个受训人员将参与重要的原创性研究和 学习基本技能，以发展成功和独立的学术生涯。其他内容 每个学员课程的各个方面将由项目主任和首席导师量身定制 根据选定的主要研究轨道以及他/她的技能、背景和职业目标。我们 提出五个主要研究方向：(1)转化医学和临床试验；(2)临床和 病床边，(3)眼科基因组和蛋白质组学，(4)眼科病理学，(5) 结果和卫生政策。由于眼科病理学家的国际短缺，我们将 试图招募和适当的个人从事涉及眼组织使用的研究事业 来源于患者和实验模型。 公共卫生相关性：

DESCRIPTION (provided by applicant): This is an institutional training grant proposal to educate the next generation of clinician-scientists for academic positions in Ophthalmology. For over 38 years, the Duke University Eye Center (DUEC) has been a national leader in training academic Ophthalmologists. The earliest generations of these trainees now serve in numerous leadership positions in academic medical centers across the country and abroad. They have roles as Deans, Department Chairs, and faculty members and serve as mentors for academicians. We propose to continue this tradition through an intensive program designed to provide the guidance, resources, and didactic teaching necessary to produce clinician-scientists for academic positions in Ophthalmology. We plan to select two trainees each year after their completion of a residency in Ophthalmology or Pathology for an intense 3 year educational program that will lead to independent peer-reviewed grant funding and a faculty position in an academic institution. The trainees will undergo an intensive didactic curriculum combined with a close mentorship by senior faculty at Duke University. Each trainee will receive mandatory training in areas of clinical research, genetics, statistics, scientific writing, grant preparation, ethics, and the responsible conduct of research. Each trainee will participate in significant original research and learn the essential skills to develop a successful and independent academic career. Additional aspects of the curriculum of each trainee will be tailored by the program director and lead mentor based upon the selected primary research track and his/her skills, background and career goals. We propose five primary research tracks: (1) translational medicine and clinical trials, (2) clinics and bedside to the bench, (3) Ophthalmic genomics and proteomics, (4) ophthalmic pathology, (5) outcomes and health policy. Because of an international shortage of Ophthalmic Pathologists we will attempt to recruit and appropriate individuals for a research career involving the use of ocular tissues derived from patients and experimental models. PUBLIC HEALTH RELEVANCE: