Personal Ozone Monitor

描述（由申请人提供）：在本提案中，我们响应国家环境健康科学研究所（NIEHS）在PHS 2009-2年综合征集，暴露生物学计划，第1部分，产生精确测量环境暴露的技术，用于“新产品/设备，工具，分析，以提高我们精确测量个体环境暴露的能力，具有高时间和空间分辨率。”根据征求意见，该设备应具有适当的规模，以便现场部署和/或可穿戴。在光化学空气污染中形成的臭氧对人类健康有充分的不利影响，包括降低肺功能和加重先前存在的呼吸系统疾病，如哮喘。在高臭氧浓度期间，急诊科就诊次数、每日住院次数和死亡率增加。个人臭氧监测仪（POM）用于臭氧的生理影响的环境卫生研究和验证人体接触的计算机模型。在第一阶段项目中，我们成功开发了一种小型（4 x 3 x 1.5英寸），重量轻（0.7磅），低功耗（2.9瓦），低成本（零件795美元），电池供电的POM，基于完善的紫外线吸收方法（EPA联邦参考方法）。口袋大小的POM具有# 2ppb的精度和准确度，每10秒进行一次新的测量，并有一个内部数据记录器，用于将数据下载到个人电脑。在此建议的第二期项目期间，我们将进一步完善和完成POM的发展，包括以下内容：1)印刷电路板上的专用接地面进一步降低噪音，2)坚固耐用，易于制造的外壳，3)由液晶显示器和键盘组成的人机界面，4)带电池充电器的对接站，5)GPS与地理坐标共同定位测量，6)POM与对接站之间的无线通信。将开发固件以支持这些新功能，并将开发软件以供计算机获取数据和绘图以及将臭氧数据上传到网络。将在新泽西医学和牙科大学环境与职业健康科学研究所（EOHSI）进行的个人接触监测研究中评估POM的功效和准确性。除了个人臭氧监测外，还确定了几个口袋大小的臭氧监测仪的大市场；其中包括迅速增长的臭氧工业应用和“全球臭氧计划”（GO3）。“全球臭氧计划”是一项国际教育计划，中学生在该计划中建立和操作一个臭氧监测站，并在“谷歌地球”地图上分享他们的数据。

DESCRIPTION (provided by applicant): In this proposal we respond to the call by the National Institute of Environmental Health Sciences (NIEHS) in the PHS 2009-2 Omnibus Solicitation, Exposure Biology Program, Section 1, Technologies for Generating Precise Measures of Environmental Exposures for "new products/devices, tools, assays to improve our ability to precisely measure environmental exposures to individuals with high temporal and spatial resolution." According to the solicitation, the device should be of appropriate scale to be field deployable and/or wearable. Ozone, formed in photochemical air pollution, has well documented adverse effects on human health, including reduction of lung function and aggravation of preexisting respiratory disease such as asthma. Emergency department visits, daily hospital admissions and mortality increase during episodes of high ozone concentration. A Personal Ozone Monitor (POM) is required for environmental health studies of the physiological effects of ozone and for validating computer models of human exposure. In the Phase I project we successfully developed a small (4 x 3 x 1.5 inch), light weight (0.7 lb), low power (2.9 watts), low cost ($795 in parts), battery-operated POM based on the well established method of UV absorbance (an EPA Federal Reference Method). The pocket-sized POM has a precision and accuracy of # 2 ppb, makes new measurements every 10 s and has an internal data logger for downloading data to a personal computer. During the Phase II project proposed here, we will further improve and finalize the development of the POM to include the following: 1) dedicated ground plane on the printed circuit board to further reduce noise, 2) ruggedized, easily manufactured enclosure, 3) human interface consisting of liquid crystal display and keypad, 4) docking station with battery charger, 5) GPS for co-locating measurements with geographical coordinates, and 6) wireless communication between the POM and docking station. Firmware will be developed to support the new functions, and software will be developed for data acquisition and graphing by a computer and for uploading ozone data to the web. The efficacy and accuracy of the POM will be evaluated in personal exposure monitoring studies conducted at the Environmental and Occupational Health Sciences Institute (EOHSI) of the University of Medicine and Dentistry of New Jersey. Several large markets for a pocket-sized ozone monitor have been identified in addition to personal ozone monitoring; these include rapidly growing industrial applications of ozone and the Global Ozone (GO3) Project, an international educational project in which high school students build and operate an ozone monitoring station and share their data as an overlay on the Google Earth" map. PUBLIC HEALTH RELEVANCE: Development of a pocket-sized, battery powered Personal Ozone Monitor (POM) will be completed and evaluated as a means of measuring the time-resolved exposure of individuals during normal daily activities. The POM will facilitate physiological studies of the adverse effects of ozone, formed in air pollution, on human health.