2014 Bioelectrochemistry Gordon Research Conference & Gordon Research Seminar

描述（由申请人提供）：本修订提案要求部分支持将于2014年7月5日至11日在缅因州比德福德的新英格兰大学举行的戈登研究会议和戈登生物电化学研究研讨会。会议主题是“细胞和有机体对内源性和外源性领域的反应”。会议的主要目标是从详细了解电场中的复杂膜到激动人心的新的临床应用，包括电化疗、基因电转移以及伤口愈合和诊断应用。本次会议的具体目标是召集35名跨学科演讲者和讨论领导者，代表电场/组织相互作用研究的前沿，共有140名参与者或在9个重点会议期间进行深入讨论。作为一个特别的特点，计划举办一次戈登研究研讨会，目的是让年轻的研究人员在实际的戈登会议开始前24小时内见面并展示他们的成果。预计将有50名博士后、临床研究员和博士生参加本次研讨会。会议将以一个强大的演讲团队开始，讨论细胞膜和电场之间的相互作用，因为它们与癌症中正常和异常的细胞发育以及伤口愈合和干细胞迁移有关。接下来的课程包括细胞内成分对电场的反应及其对细胞和组织的影响。随后的会议侧重于应用电场及其在基因和药物传递中的应用，重点是基础机制研究。一个由研究人员和医生组成的小组参与了基于电穿孔疗法（如电疗和基因电转移）的临床试验，将从基础科学到实际临床应用的讨论架起桥梁。

DESCRIPTION (provided by applicant): This revised proposal requests partial support for the Gordon Research Conference and Gordon Research Seminar on Bioelectrochemistry to be held at the University of New England in Biddeford, Maine between July 5 to 11, 2014. The meeting theme is "Cellular and organismal responses to endogenous and exogenous fields". The broad goal of the conference is to draw a direct line from a detailed understanding of the complex membrane in the electric field to exciting new clinical applications with electrochemotherapy, gene electrotransfer, as well as wound healing and diagnostic applications. The specific aim of this meeting is to convene 35 cross-disciplinary speakers and discussion leaders representing the forefront of research into electric field/tissue interactions with a total of 140 participants or in depth discussions during 9 focused sessions. As a particular feature, a Gordon Research Seminar, intended for young researchers to meet and present their results in the 24 hours before the actual Gordon Conference starts, is envisaged. A total of 50 postdoctoral fellows, clinical fellows, and Ph.D. students are anticipated to attend the seminar. The conference will commence with a strong team of speakers discussing interactions between the cell membrane and electric fields as they pertain to normal and aberrant cellular development in cancer as well as wound healing and stem cell migration. Sessions to follow include those on the responses on intracellular components to electric fields and their consequences on cells and tissues. Subsequent sessions focus on applied electric fields and their use for gene and drug delivery, with an emphasis on basic mechanistic studies. A panel of researchers and doctors involved in clinical trials on electroporation based therapies (such as electrochemotherapy and gene electrotransfer) will bridge the discussion from basic science to actual clinical application.