Eastern Cooperative Oncology Group

描述(由申请人提供)：这笔赠款的主要目标是获得资金，以支持范德比尔特大学医学中心东部合作肿瘤学小组(ECOG)的临床研究活动，促进患者在ECOG试验中的收益，并扩大Vanderbilt研究人员对ECOG的科学和行政贡献。该建议的具体目标是：1)增加对ECOG赞助的临床试验的参与，2)进一步增加Vanderbilt研究人员对ECOG的科学和行政贡献，3)继续开发常见实体肿瘤和血液恶性肿瘤的创新治疗计划，4)为ECOG试验的相关实验室项目提供基础科学专业知识，5)保持高水平的数据质量和管理，该机构以此而闻名。这些目标将通过来自医学肿瘤学、放射肿瘤学、病理学和外科科学科的研究人员的密切互动来实现。范德比尔特公司和其他经社理事会机构之间的互动将通过范德比尔特公司在经社理事会疾病导向和模式委员会的调查人员的出席而得到便利。范德比尔特-英格拉姆综合癌症中心具备成功实施合作小组临床试验的所有必要要素，包括优秀的数据管理人员、开展这项工作的优秀门诊和住院设施以及长期参与合作小组的历史。

DESCRIPTION (provided by applicant): The principal objectives of this grant are to secure funding to support the clinical research activity of the Eastern Cooperative Oncology Group (ECOG) at Vanderbilt University Medical Center, to facilitate patient accrual to ECOG trials, and to expand the scientific and administrative contributions made to ECOG by Vanderbilt investigators. The specific aims of the proposal are: 1) to increase participation in ECOG sponsored clinical trials, 2) to further increase the scientific and administrative contributions to ECOG by Vanderbilt investigators, 3) to continue the development of innovative treatment programs for common solid tumors and hematologic malignancies, 4) to provide basic science expertise for correlative laboratory projects attached to ECOG trials and 5) to maintain a high level of data quality and management for which this institution is known. These goals will be achieved through the close interaction of investigators from medical oncology, radiation oncology, pathology and the section of surgical sciences. The interactions between Vanderbilt and other ECOG institutions will be facilitated by the presence of Vanderbilt investigators on ECOG disease oriented and modality committees. The Vanderbilt-lngram Comprehensive Cancer Center has in place all the necessary elements for the successful execution of cooperative group clinical trials including an outstanding data management staff, excellent outpatient and inpatient facilities in which this work will be undertaken and a long history of cooperative group participation.