Training Program in Oncogenic Signals and Chromosome Biology

描述（由申请人提供）：这是加州大学戴维斯分校致癌信号和染色体生物学博士后T32项目的第一个续签申请。该培训项目利用了加州大学戴维斯分校nci指定癌症中心分子肿瘤学项目的综合优势，以及参与教师在致癌信号和染色体生物学方面的卓越专业知识和培训记录。该项目涉及30名培训师，其中包括三名国家科学院成员，他们也是分子肿瘤学项目的骨干。每个培训师都有一个积极的、外部资助的研究项目。参与的教师代表不同的学科，但有一个共同的主题焦点。在加州大学戴维斯分校临床和转化科学中心的进一步支持下，癌症中心强大的临床研究组成部分促进了该计划的转化方面。在第一个资助期内，该培训项目吸引了12名才华横溢的博士后来到加州大学戴维斯分校。值得注意的是，其中5名研究员已经获得了竞争非常激烈的NIH、DOD和CBCRP的个人奖学金，继续他们在癌症生物学方面的培训。该培训计划开发了一系列创新和有效的课程活动，提供致癌信号和染色体生物学方面的正式培训，负责任的研究行为教育以及个人指导。丰富多样的研讨会、会议、讨论小组、讲习班和务虚会提供了展示研究进展的机会，并拓宽了培训师实验室之外的培训经验。该培训项目在支持受训人员的基础上增加了显著的价值，因为它为117人提供了服务，其中包括39名符合培训资助资格的博士后，他们积极参与一些培训资助活动。一个有效的行政结构已经到位，在这次更新中得到进一步完善。在一个积极的执行委员会的指导下，一名主任和一名联合主任管理这个项目。执行委员会的每个成员都积极维护一个特定的投资组合，以加强计划活动。为了进一步发展培训计划，我们成立了一个四人顾问委员会。这两名外部顾问是类似癌症导向培训项目的主管，其中一名还担任加州大学戴维斯分校癌症中心外部顾问委员会成员，负责分子肿瘤学项目。这两名内部成员都是经验丰富的导师，其中包括医学院的执行副院长，他是培训和指导方面的权威。该培训计划旨在为学员在学术或研究机构、生物技术行业或政府实验室的独立研究事业做好准备。

DESCRIPTION (provided by applicant): This is the first renewal application for the UC Davis postdoctoral T32 program in Oncogenic Signals and Chromosome Biology. This training program takes advantage of the integrated strength of the Molecular Oncology Program at the UC Davis NCI-designated Cancer Center and the exceptional expertise and training records of the participating faculty members in oncogenic signals and chromosome biology. The program involves 30 trainers, including three National Academy members, who also form the backbone of the Molecular Oncology Program. Every trainer maintains an active, extramurally funded research program. The participating faculty members represent diverse disciplines but share a common topical focus. A strong clinical research component at the Cancer Center facilitates the translational aspect of this program, with further support from the UC Davis Clinical and Translational Science Center. Over the first funding period, the training program attracted an outstanding cohort of 12 highly talented postdoctoral fellows to UC Davis. Remarkably, five of these fellows have already moved on to very competitive, individual fellowships from NIH, DOD, and CBCRP to continue their training in cancer biology. The training program has developed an innovative and effective array of curricular activities that provide formal training in oncogenic signals and chromosome biology, education in the responsible conduct of research, and individual mentoring. A rich and diverse array of seminars, conferences, discussion groups, workshops, and retreats provide opportunities to present research progress and broaden the training experience beyond the trainer's laboratory. The training program added significant value above supporting trainees, as it serviced a cohort of 117, including 39 training grant eligible, postdoctoral fellows, who actively participate in some training grant activities. An effective administrative structure is in place that is further refined in this renewal. A director and a co-director administer the program, with guidance by an active executive committee. Each member of the executive committee actively maintains a specific portfolio to enhance the program activities. To further develop the training program, we have created a four-member Advisory Board. The two external advisors are directors of comparable cancer-oriented training programs, and one also serves on the External Advisory Board of the UC Davis Cancer Center with responsibility for the Molecular Oncology Program. The two internal members are highly experienced mentors and include the Executive Associate Dean of the School of Medicine, who is an authority in training and mentoring. The training program aims to prepare our trainees for independent research careers in academic or research institutions, biotechnology industries, or government laboratories. PUBLIC HEALTH RELEVANCE: This is the first renewal application of the UC Davis T32 postdoctoral training grant in Oncogenic Signals and Chromosome Biology, which is associated with the Molecular Oncology Program of the NCI-designated UC Davis Cancer Center. The program has developed a thriving and innovative training environment as well as an effective administrative infrastructure that has been very successful in attracting 12 highly qualified postdoctoral fellows to UC Davis. The next funding period aims to build upon this success and to further refine the program to prepare our postdoctoral trainees for independent research careers in academic or research institutions, biotechnology industries, or government laboratories.