Baboon Research Resource Program

描述(由申请者提供)：OUHSC浣熊资源计划继续作为NIH支持的生物医学和行为研究的国家狒狒来源。在过去的四年里，我们已经向俄克拉荷马大学健康科学中心以外的23个机构提供了582只狒狒。在过去的四年里，我们还为发展中的OUHSC无特定病原体(SPF)狒狒计划提供了110只狒狒。这个SPF菌落是独一无二的，也是NIH唯一已知的13种内源性病毒阴性的狒狒菌落，其中包括所有已知的5种狒狒疱疹病毒、4种逆转录病毒以及其他4种狒狒病毒和最常见的狒狒寄生虫。我们继续朝着自给自足的方向取得重大进展，因为项目收入提供了狒狒研究资源项目近50%的支持。随着耗资650万美元、占地1.8万平方英尺的新Bobon SPF大楼的竣工，我们的基础设施取得了重大进展。我们与俄克拉何马州立大学兽医健康科学中心(OSUHSC)(兽医学院)的合作继续产生大量与研究资源相关的研究。这个应用程序有一个明显更强大的行为和遗传程序，增加了一名博士级别的遗传行为学家(John Ely，博士)。我们现在正在进行内部病毒诊断，并增加了一名全职博士级别的病毒学家(James Papin，博士)。最近，我们的比较医学系增加了一名全职兽医免疫学家(苏尼尔·乔希，DVM，博士)。这三名全职研究和诊断人员显著加强了我们在行为、基因组学、病毒学和免疫学方面的诊断和研究专业知识。OHSC袋熊研究资源计划继续吸引更多的兽医学生导师。在过去的四年里，我们有来自七所兽医学校的兽医学生导师和来访的暑期学生。我们继续为来自俄克拉何马州立大学、密苏里大学和堪萨斯州立大学的NIH T 35学生举办暑期访问和旅游。OUHSC浣熊研究资源继续作为生物医学和行为研究的全国性资源。

DESCRIPTION (provided by applicant): The OUHSC Baboon Resource Program continues to serves as a national source of baboons for NIH supported biomedical and behavioral research. Over the last four years we have provided 582 baboons to 23 Institutions outside the University of Oklahoma Health Sciences Center. We have also provided 110 baboons over the last four years for the developing OUHSC Baboon Specific Pathogen Free (SPF) baboon program. This SPF colony is unique and is the only known NIH baboon colony that is negative for 13 endogenous viruses including all five known baboon herpes viruses, four retroviruses, plus four other baboon viruses and the most common baboon parasites. We continue to make significant progress toward self-sufficiency as the program income provides almost 50% of the support of the baboon research resource program. Significant progress has been made in our infrastructure with the completion of the new state of the art 6.5 million dollar, 18,000 square foot Baboon SPF building. Our collaboration with the Oklahoma State University Center for Veterinary Health Sciences (OSUHSC) (College of Veterinary Medicine) continues to produce significant research resource related research. This application has a significantly stronger behavioral and genetic program with the addition of a PhD level genetic behaviorist (John Ely, PhD). We are now performing in house viral diagnostics with the addition of a full time PhD level Virologist (James Papin, PhD). Recently we have added a full time Veterinary Immunologist to our Comparative Medicine Faculty (Sunil Joshi, DVM, PhD). These three full time research and diagnostic faculty significantly strengthens our diagnostic and research expertise in behavior, genonomics, virology, and immunology. The OUHSC Baboon Research Resource program continues to attract more veterinary student preceptors. Over the last four years we have had veterinary student preceptors and visiting summer students from seven veterinary schools. We continue to host a summer visit and tour for NIH T 35 students from, Oklahoma State University, University of Missouri, and Kansas State University. The OUHSC Baboon Research Resource continues to serve as a national source for biomedical, and behavior research.