National Emerging Infectious Diseases Laboratories Operations

描述（由申请人提供）： 国家新发传染病实验室（NEIDL）研究所的总体目标是做出基本发现，从而预防和控制世界上新发和再发的传染病。传染病是世界范围发病率和死亡率最容易改变的一个原因，影响到全球人口的很大一部分，对婴儿、儿童和处于最高生产年龄的成年人造成特别严重的损失，对家庭以及地方和全球经济造成破坏性影响。利用全方位的尖端研究技术平台，与创新的教师和战略性的国内和国际合作者聚集在一个地方，NEIDL研究所旨在通过合作研究团队的努力，解决预防和控制新出现的传染病的关键和基本的知识障碍。NEIDL建立在这样一种理念之上，即在高度封闭的环境中为免疫学、微生物学、遗传学和传染病领域的专家提供现代科学学科的发现工具箱，并专注于传染病发现研究，这将是早期研究最令人兴奋和最富有成效的框架，最终将导致疫苗的开发，治疗和新兴传染病的控制措施。一系列全面的研究技术和传染病模型可用于应对最关键的新出现的传染病，包括流感（包括高致病性和流行性菌株）、结核病（包括多重和广泛耐药菌株）、蚊子和蜱虫传播的传染病（包括出血热和脑炎病毒）以及抗生素耐药病原体。最先进的约192，000平方英尺的设施在设计时高度重视安全和安保。NEIDL设施设有高密封BSL-4研究实验室和相关的支持实验室，机械，临床研究和行政空间。该研究所由十八个核心组成，代表五个功能领域，所有这些都支持BSL-4实验室。这些核心分为5个领域，包括设施维护和运营、生物安保、环境健康和安全法规和要求、法规遵守以及综合研究支持服务。

DESCRIPTION (provided by applicant): The overall goal of the National Emerging Infectious Diseases Laboratories (NEIDL) Institute is to make fundamental discoveries that lead to the prevention and control of the world's emerging and re-emerging infectious diseases. Infectious diseases are the single most modifiable cause of worldwide morbidity and mortality affecting large sectors of the global population and exacting a particularly heavy toll on infants, children and adults in their most productive years, with devastating effects on families and local and global economies. Using the full spectrum of cutting edge research technology platforms assembled in one location with innovative faculty and strategic domestic and international collaborators the NEIDL Institute seeks to address critical and fundamental knowledge barriers to the prevention and control of emerging infectious diseases through the efforts of collaborating research teams. The NEIDL Is built on the philosophy that making available in high containment the discovery toolboxes of modern scientific disciplines to experts in immunology, microbiology, genetics and infectious diseases with a singular focus on infectious diseases discovery research will be the most exciting and productive framework for early stage research that will ultimately lead to the development of vaccines, treatments and control measures for emerging infectious diseases. A comprehensive array of research technologies and infectious disease models can be brought to bear on the most critical emerging infectious diseases including influenza (including highly pathogenic and epidemic strains), tuberculosis (including multi- and extensive drug resistant strains), mosquito and tick insect transmitted infectious diseases (including hemorrhagic fever and encephalitis viruses), and antibiotic resistant pathogens. The state of the art approximately 192,000 sq ft facility is designed with the highest attention to safety and security. The NEIDL facility houses high containment BSL-4 research laboratories and associated support laboratories, mechanical, clinical research and administrative spaces. The Institute is comprised of eighteen cores which represent five functional areas, all of which support the BSL-4 laboratories. These Cores are grouped under 5 areas that include facility maintenance and operations, biosecurity, environmental health and safety regulations and requirements, regulatory compliance, and integrated research support services.