课题基金 / 基金详情

TAS::75 0872::TAS PROTEOME BIOLOGY OF CARDIOVASCULAR DISEASE

TAS::75 0872::TAS PROTEOME BIOLOGY OF CARDIOVASCULAR DISEASE
TAS::75 0872::TAS 心血管疾病蛋白质组生物学
批准号：
8175614
负责人：
Peipei Ping
金额：
$227.35万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-08-15 至 2015-08-14
来源：
https://reporter.nih.gov/project-details/8175614
关键词：
BiologyCardiovascular DiseasesProteome

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中文摘要
翻译
加州大学洛杉矶分校蛋白质组学中心的总体目标是通过表征正常和疾病心肌中线粒体和蛋白酶体的核心细胞器成分来获得对心血管疾病的机制和功能见解。此外，调节这些细胞器的分子途径将被描绘为确定新的治疗靶点的最终目标。
英文摘要
The overall goal of the UCLA Proteomics Center is to gain mechanistic and functional insights into cardiovascular disease through characterization of the core organelle constituents of the mitochondria and proteasome in normal and diseases myocardium. Additionally, molecular pathways that regulate these organelles will be delineated with the ultimate goal of identifying novel therapeutic targets.
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会议论文
The 2022 Annual Conference of ISHR-NAS: Advances in Cardiovascular Medicine Through Diversity, Equity, and Inclusion; Focusing on Education and Technological Innovation
Omics Phenotyping for Identifying Molecular Signatures of the Healthy and Failing Heart: An Integrated Data Science Platform
Omics Phenotyping for Identifying Molecular Signatures of the Healthy and Failing Heart: An Integrated Data Science Platform
Regulation of Protein Dynamics in Heart Failure
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