Pacific Center for Emerging Infectious Diseases Research

 简介(由申请者提供)：太平洋新兴传染病研究中心成立于2003年，是一个由机构发展奖(IDEA)计划中的生物医学研究卓越中心(Cobre)资助的翻译科学卓越中心，旨在为新的、新兴的和重新出现的传染病开发和部署快速诊断、改进的疗法和负担得起的疫苗，这些传染病对亚太地区服务不足的社区造成了不成比例的影响。科布雷中心还寻求通过培训和指导夏威夷原住民和其他代表性不足的太平洋岛民来增加生物医学研究劳动力的多样性。因此，该中心的使命与国家普通医学科学研究所的使命完全一致，即支持为疾病诊断、治疗和预防的进步奠定基础的基础研究，并通过支持下一代科学家的培训来增加研究队伍的多样性。(http://www.nigms.nih.gov/About/Pages/default.aspx).新发传染病防治中心第三阶段的主要目标是改善条件，加快科学发现的步伐，提高研究生产率，并提高争取外部资金的竞争力。这一目标将通过(1)增强Cobre核心在生物遏制、生物信息学以及分子和细胞免疫学方面的增长和可持续性，这些核心建立在定制和协作服务、研发以及教育和培训三位一体的基础上；以及(2)制定和实施Cobre小额赠款计划，无国界地促进合作和伙伴关系，促进数据和资源共享，并提供更多机会，在旨在改善人类健康的研究中，在IDEA资助的中心之间进行指导和专业培训。COBRE在第一和第二阶段的资助改变了指导和培训未来几代研究人员的格局，并为关于流行病的多学科合作研究提供了最先进的核心资源。在机构层面，科布雷资助促使人们做出重大承诺，招聘和留住新的生产性教员队伍，这种努力将持续到第三阶段。高层行政机构的承诺将确保中心及其核心在第三阶段科布雷之后的可持续性。

 DESCRIPTION (provided by applicant): Established in 2003, the Pacific Center for Emerging Infectious Diseases Research, a translational science center of excellence supported by funding from the Centers of Biomedical Research Excellence (COBRE) component of the Institutional Development Award (IDeA) program, seeks to develop and deploy rapid diagnostics, improved therapeutics and affordable vaccines for new, emerging and re-emerging infectious diseases that disproportionately affect underserved communities in the Asia-Pacific region. The COBRE Center also seeks to increase the diversity of the biomedical research workforce by training and mentoring native Hawaiians and other underrepresented Pacific Islanders. Thus, the Center's mission is thoroughly consistent with that of the National Institute of General Medical Sciences, which is to support basic research that lays the foundation for advances in disease diagnosis, treatment and prevention, and to increase the diversity of the research workforce by supporting the training of the next generation of scientists (http://www.nigms.nih.gov/About/Pages/default.aspx). The principal objective of the Phase III COBRE for emerging infectious diseases is to enhance the conditions that accelerate the pace of scientific discovery, heighten research productivity and increase competitiveness for extramural funding. The objective will be achieved by (1) enhancing the growth and sustainability of the COBRE cores in biocontainment, bioinformatics, and molecular and cellular immunology, which are grounded in the triad of customized and collaborative service, research and development, and education and training; and (2) developing and implementing a COBRE Small Grants Program, without borders, that fosters collaborations and partnerships, promotes data and resource sharing, and provides additional opportunities for mentoring and specialized training across IDeA-funded centers in research aimed at improving human health. COBRE funding during Phases I and II has transformed the landscape for mentoring and training future generations of investigators and has provided state-of-the-art core resources for multi-disciplinary collaborative research on epidemic infectious diseases. At the institutional level, COBRE funding has spurred significant commitments to recruit and retain a new cadre of productive faculty, and such efforts will continue into Phase III. High-level upper-administrative institutional commitments will ensure the sustainability of the Center and its cores beyond the Phase III COBRE period.