An alternate function of the microRNA biogenesis machinery

控制基因的活动至关重要。过多或过少都会导致细胞不能正常工作。我们发现了一种控制基因的新方法。我们发现一种叫做Drosha的酶可以通过切断这些基因的产物来防止某些基因的过度激活。这种控制基因的方式似乎对发育过程特别重要，比如发生在胚胎中。我们的目标是在分子水平上精确地理解这种机制。

Controlling the activity of genes is crucial. Too much or too little can result in a cell not functioning properly. We have discovered a new way genes are controlled. We have found that an enzyme called Drosha can prevent too much activation of some genes by chopping up the products of these genes. This way of controlling genes appears to be especially important for developmental processes, such as occurs in the embryo. Our goal is to understand this mechanism precisely at the molecular level.