The associations between cognitive decline and genetic polymorphisms, hormones and cardiovascular risk factors in women.

痴呆症是老年女性发病率和死亡率的主要原因，它与荷尔蒙变化和基因有关。如果能够确定与认知受损和早期阿尔茨海默病相关的因素，那么就可以为那些有风险的人提供早期干预。在这项研究中，我们确定了遗传、医学和生活方式因素，这些因素可能与绝经前到绝经后女性的认知能力下降和早期阿尔茨海默病有关。

Dementia, a major cause of morbidity and mortality in ageing women, has been linked to hormonal changes and genes. If factors associated with impaired cognition and early Alzheimer's disease could be identified then early interventions could be offered to those at risk. In this study we determine the genetic, medical and lifestyle factors which may be associated with cognitive decline and early Alzheimer's disease in women from pre-menopause into their post-menopausal years.