The Darwin Prospective Melioidosis Study: Years 27-31

自1989年以来，达尔文前瞻类梅毒研究已经记录了914例，其中115人死亡。达尔文类鼻炎病例在过去5年中的激增与城市发展和一种新细菌株的发现有关。我们独特的25年以上的细菌及其相关患者数据的全基因组测序将揭开不断变化的流行病学并识别重要的毒力因素，为未来的诊断、治疗和疫苗奠定基础。

The Darwin Prospective Melioidosis Study has documented 914 cases since 1989, with 115 fatalities. A surge in Darwin melioidosis cases over the past 5 years has been linked to urban development and the discovery of a new bacterial strain. Whole genome sequencing of our unique 25+ year set of bacteria and their linked patient data will unravel the changing epidemiology and identify important virulence factors, forming a foundation for future diagnostics, therapeutics, and vaccines.