The differential innervation of fat - potential to target visceral adiposity

腹部脂肪水平与代谢综合征密切相关。我们建议通过实验来确定大脑深处神经元的独特特征（神经递质或受体），这些特征专门针对这种类型的脂肪或其他危害较小的皮下脂肪。然后，我们可以在动物实验中测试这些独特元素的功能意义，包括基因敲除或药理学方法来改变它们的功能，并测试对脂肪分布的影响

Levels of abdominal fat are closely correlated with metabolic syndrome. We propose experiments to identify unique characteristics (neurotransmitters or receptors) of neurons deep in the brain that project specifically to this type of fat or other less harmful subcutaneous fat. We can then test the functional significance of these unique elements in animal experimets involving gene knockdown or pharmacological approaches to modify their function and test the effect on fat distribution