The generation, fate and functional potential of recent thymic emigrants

一种名为T淋巴细胞的特殊白细胞负责控制我们对外来入侵者的免疫反应。这些细胞在胸腺中发育，在移居到其他器官之前，它们在那里学习区分外来入侵者和自身组织。这一过程的调节对于维持体内的T淋巴细胞池非常重要。重要的是，T淋巴细胞不会对自身组织产生反应，因为这会导致一种称为自身免疫的自体破坏性疾病。由于这些发育中的T淋巴细胞在胸腺中看不到各种自身组织，我们建议它们在离开胸腺后继续进行一段时间的教育，以防止自身组织的反应性。

A particular kind of white blood cell, called a T lymphocyte, is responsible for controlling our immune responses to foreign invaders. These cells develop in the thymus, where they learn to distinguish between foreign invaders and self tissue, before emigrating to other organs. The regulation of this process is important to maintain a pool of T lymphocytes in the body. It is important that T lymphocytes do not respond against self tissue, as this can lead to a Oself destructO disease called autoimmunity. Since these developing T lymphocytes will not see all kinds of self tissue while in the thymus, we propose that their education to prevent self-tissue reactivity may continue for some time after they leave the thymus.