Australasian Malignant Pleural Effusion (AMPLE)-3 trial

癌症会扩散到肺部，导致液体积聚，需要在医院进行引流，这是痛苦和昂贵的。手术以前被认为是阻止液体形成的最终选择，但具有侵入性，有并发症。留置胸膜导管(IPC)是一种新型的胸腔内植入装置，可以让患者在家中排出液体。Ample Trial-3是第一个多中心随机临床试验，比较了手术和IPC在提供液体控制和改善生活质量方面的作用。

Cancers can spread to the lung causing fluid build-up and requires drainages in hospital that are painful and costly. Surgery is previously seen as the definitive option to stop fluid forming, but is invasive with complications. Indwelling pleural catheter (IPC) is a novel implanted device inside the chest that allows patients to drain fluid at home. AMPLE Trial-3 is the first multicenter randomized clinical trial to compare surgery vs IPC to provide fluid control and improve quality of life.