Fluorimeter upgrade
Fluorimeter upgrade
批准号:
344472-2007
负责人:
Bohne, Cornelia
金额:
$0.94万
依托单位:
依托单位国家:
加拿大
项目类别:
Research Tools and Instruments - Category 1 (<$150,000)
财政年份:
2006
资助国家:
加拿大
项目状态:
已结题
起止时间:
2006-01-01 至 2007-12-31
关键词:
中文摘要
荧光是分子吸收不同颜色的光(能量更高,波长更短)后发光的一种性质。这种荧光测量非常敏感,在其极限发射下可以从单个分子中检测到。由于其敏感性,荧光已经找到了许多应用,例如,在医学诊断试剂盒的传感器中。现代化学家将荧光用作反应发生效率的诊断工具,并用作了解分子如何相互作用的探针。在Bohne群中,荧光是建立客体与超分子系统结合方式的基本工具。这一表征先于所有动力学研究,以确定客体与宿主系统的结合动力学。此外,复杂体系的荧光研究的专门知识和能力一直是Bohne小组与日本和德国研究人员合作的中心主题。万组专门研究光化学反应是如何发生的。许多化合物在吸收光(光化学的启动过程)后和反应前经历荧光,这种发射被用作反应效率的诊断工具。这两个研究小组目前使用的荧光仪已有10年的历史,数据采集和分析是在安装了专有DOS软件的旧电脑上进行的。因此,要求升级将消除荧光数据获取的瓶颈,并将提高相关小组的生产率。
英文摘要
Fluorescence is a property where molecules emit light after absorbing light of a different color (higher energy, shorter wavelength). Fluorescence measurements are very sensitive and at its limit emission can be detected from a single molecule. Because of its sensitivity fluorescence has found many applications, as for example in sensors in medical diagnostic kits. Chemists use fluorescence as a diagnostic tool for how efficiently reactions happen and as probes to understand how molecules can interact with one another. In the Bohne group fluorescence is an essential tool to establish how guests bind to supramolecular systems. This characterization precedes all of the kinetic studies to determine the binding dynamics of guests to host systems. In addition, the expertise and ability for fluorescence studies of complex systems has been the central theme for the collaboration of the Bohne group with researchers in Japan and Germany. The Wan group specializes in studying how photochemical reactions happen. Many of the compounds after absorbing light (initiation process for photochemistry) and before reacting undergo fluorescence and this emission is used as a diagnostic tool for the efficiency of the reactions. The current fluorimeter used by both research groups is 10 years old and data acquisition and analysis is performed on an old computer with proprietary DOS software. The request for an upgrade would eliminate the bottleneck in the acquisition of fluorescence data and would enhance the productivity of the groups involved.
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Supramolecular Dynamics in Solution and in Gels
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资助金额:$5.39万
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资助金额:$5.39万
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资助金额:$5.39万
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财政年份:2017
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依托单位:
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财政年份:2016
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依托单位:
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资助金额:$5.1万
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财政年份:2015
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负责人:Bohne, Cornelia
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依托单位:
Dynamics of Small Molecules in Supramolecular Systems
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批准号:121389-2012
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.1万
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财政年份:2014
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负责人:Bohne, Cornelia
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依托单位:
Dynamics of Small Molecules in Supramolecular Systems
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批准号:121389-2012
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资助金额:$5.1万
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财政年份:2013
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依托单位:
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资助金额:$5.1万
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财政年份:2012
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资助金额:$1.93万
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财政年份:2011
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依托单位:
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依托单位:
Supramolecular dynamics
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批准号:121389-2007
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.68万
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财政年份:2010
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依托单位:
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资助金额:$1.69万
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财政年份:2010
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依托单位:
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项目类别:Discovery Grants Program - Individual
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资助金额:$5.68万
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财政年份:2009
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依托单位:
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依托单位:
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依托单位:
海外基金