A POPULATION-BASED COHORT INVESTIGATION OF LUNG FUNCTION IN RELATION TO EARLY LIFE LOWER RESPIRATORY TRACT ILLNESS AND AEROALLERGN SENSITISATION

婴儿期似乎是肺结构和功能发生重要变化的关键发育窗口期。在这项研究中，我们将评估早期肺功能如何演变与潜在的损害，如下呼吸道感染和过敏性炎症。这些都是哮喘被认为发展的机制。我们将使用令人兴奋的新肺功能测试来评估与慢性气道疾病（如哮喘）周围功能障碍特征相关的肺功能异常。

Infancy appears to be the critical developmental window during which important alterations in lung structure and function develop. In this study we will assess how early lung function evolves in relation to potential insults such as lower respiratory tract infections and allergic inflammation. These are the mechanisms by which asthma is thought to develop. We will use exciting new lung function tests to evaluate lung function abnormalities associated with peripheral dysfunction characteristic of chronic airway disease such as asthma.