The role of the alimentary microbiome in the development of mucositis

黏膜炎是癌症治疗的一种使人衰弱的副作用，由于缺乏对黏膜炎如何发展的了解，目前无法治疗或预防。先前的研究表明，微生物参与了动物模型粘膜炎的发展。该项目将确定口腔和肠道中的细菌是否在患者粘膜炎的发展中发挥作用，以及是否容易检测到变化，从而允许更“个性化”的方法来管理粘膜炎。

Mucositis is a debilitating side effect of cancer treatment, which is currently not treatable or preventable, due to a lack of understanding of how mucositis develops. Previous research has shown that microbes are involved in the development of mucositis in animal models. This project will determine if bacteria in the mouth and intestine play a role in the development of mucositis in patients, and if changes are easily detected, to allow for a more 'personalised' approach to manage mucositis.