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Innovative mathematical modelling to determine incorporation of gene therapy in different cell lineages; Human Immunodeficiency Virus (HIV) as a model setting

Innovative mathematical modelling to determine incorporation of gene therapy in different cell lineages; Human Immunodeficiency Virus (HIV) as a model setting
创新的数学模型,以确定基因治疗在不同细胞谱系中的结合;
批准号:
LP130100015
负责人:
Prof John Murray
金额:
$24.43万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-08-01 至 2016-08-01

项目摘要

项目成果

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中文摘要
翻译
基因治疗是一种很有前途的治疗方法,正在开发用于治疗遗传疾病和病毒感染,如人类免疫缺陷病毒(HIV)。该项目将建立数学模型,说明基因疗法如何将一种类型的细胞分化成预期的最终目标并影响疾病。
英文摘要
Gene therapy is a promising therapeutic that is being developed to address genetic diseases and viral infections such as Human Immunodeficiency Virus (HIV). This project will produce mathematical models of how gene therapy delivered to one type of cell can differentiate into the desired end target and impact disease.
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Determining features that separate groups of protein sequences
  • 批准号:
    DP180103893
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $20.78万
  • 财政年份:
    2018
  • 负责人:
    Prof John Murray
  • 依托单位:
Mathematical modelling can provide vital information on the effectiveness and practical implementation of microbicides and vaccines against HIV
  • 批准号:
    DP130100595
  • 项目类别:
    Discovery Projects
  • 资助金额:
    $20.25万
  • 财政年份:
    2013
  • 负责人:
    Prof John Murray
  • 依托单位:
Can an anti-HIV gene in blood stem cells protect from immune depletion by HIV?
  • 批准号:
    LP100100242
  • 项目类别:
    Linkage Projects
  • 资助金额:
    $25.08万
  • 财政年份:
    2010
  • 负责人:
    Prof John Murray
  • 依托单位:
海外基金