The role of oncogenes, cell death machinery and novel players in the regulation of hematopoietic stem cells, leukemogenesis and hematological disorders

这个项目的重点是血细胞的调节以及当血细胞缺陷时出现的疾病，如骨髓衰竭和白血病。它将调查参与细胞自杀的蛋白质如何影响血细胞存活、癌症治疗和血栓形成。我们将研究癌症基因和干细胞之间的联系。最终，目标是确定血液疾病的药物靶点，并开发促进健康细胞存活的新药。

This project is focused on the regulation of blood cells and the diseases that arise when they become defective, such as bone marrow failure and leukemia. It will investigate how proteins involved in cell suicide impact on blood cell survival, cancer therapy, and the formation of blood clots. The link between cancer genes and stem cells will be examined. Ultimately, the aims are to identify drug targets in hematological disorders, and develop new drugs to promote the survival of healthy cells.