GENOMIC/PHENOMIC IDENTIFICATION AND CHARACTERISATION OF NOVEL HEMATOPOIETIC REGULATORS

新型造血调节因子的基因组/表型鉴定和表征

• 批准号: DP0556154
• 负责人: Prof Benjamin Kile
• 金额: $ 29.45万
• 依托单位: The Walter and Eliza Hall Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2008-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0556154
• 关键词: GENOMIC; PHENOMIC; IDENTIFICATION; CHARACTERISATION; NOVEL

Blood cells are fundamental to health. They play a vital role in maintaining the condition of tissues and organs, fight infections and are essential players in the body's response to injury. Understanding how blood cells are produced and how they function is critical to improving the treatment of disease. With the sequencing of the genome, we now have the tools we need to find the genes controlling these processes. This project will harness the power of modern genetic technologies to dissect the role of novel genes involved in blood cell formation and function, and will open up new therapeutic opportunities for treating the many diseases associated with dysregulation of this important cell system.

血细胞是健康的基础。它们在维持组织和器官的状态，对抗感染方面发挥着至关重要的作用，并且是身体对损伤反应的重要参与者。了解血细胞是如何产生的以及它们是如何发挥作用的，对于改善疾病的治疗至关重要。随着基因组的测序，我们现在有了找到控制这些过程的基因所需的工具。该项目将利用现代遗传技术的力量来剖析参与血细胞形成和功能的新基因的作用，并将为治疗与这一重要细胞系统失调相关的许多疾病开辟新的治疗机会。