SELECTIVE VULNERABILITY IN ALZHEIMER’S DISEASE AND RELATED DISORDERS: MECHANISM OF TAU PATHOLOGY

在澳大利亚，阿尔茨海默病和相关的痴呆症影响着23万人，预计到2050年，这一数字将增长到73万。仅在保健和住宿护理方面的直接费用每年就超过66亿美元。通过识别保护阿尔茨海默病大脑中退化神经元的基因，人们将对潜在的过程有更深的了解，并将确定治疗目标，以帮助开发一种治疗这种尚未治愈的疾病的方法。

Alzheimer’s disease and related dementias affect 230,000 people in Australia, with numbers expected to grow to 730,000 by 2050. The direct costs for health and residential care alone exceed $6.6 billion per annum. By identifying genes that protect degenerating neurons in the Alzheimer brain, a deeper understanding of the underlying processes will be gained and therapeutic targets will be defined that will assist in developing a therapy for a yet uncurable disease.