Structural and functional studies on Leptospiral antigens central to pathogenesis

钩端螺旋体病，也被称为韦伊病和坎菲尔德热，是一种由钩端螺旋体感染引起的潜在致命疾病。钩端螺旋体能够感染包括牲畜和人类在内的多种动物。人类感染通常是通过接触接触过受感染动物尿液的水或植物而发生的。该项目的重点是细菌感染的关键步骤，试图了解这些细菌如何粘附在人体细胞上。

Leptospirosis, also known as Weil's disease and canefield fever, is a potentially fatal disease caused by infection with the bacteria Leptospira. Leptospira is able to infect a broad range of animals including livestock and humans. Human infection typically occurs through contact with water or vegetation that has been exposed to the urine of an infected animal. This project focuses on a key step in the bacterial infection in trying to understand how these bacteria adhere to human cells.