Surface antigens of Plasmodium falciparum-infected erythrocytes and immunity to malaria in humans

疟疾是全球死亡的主要原因，特别是在儿童中。疟疾寄生虫感染红细胞并在其中繁殖，如果不治疗，会导致严重的疾病。有效的治疗方法有限，目前还没有疫苗。在人类研究中，我们的目标是确定免疫应答的靶抗原和预防疟疾的免疫机制。有了这些知识，就可以设计出抗疟疾的疫苗，以预防严重疾病和死亡。

Malaria is a leading cause of death globally, particularly among children. Malaria parasites infect red blood cells and multiply inside them, resulting in severe illness if left untreated. Effective treatments are limited and currently there is no vaccine. In human studies, we aim to identify the target antigens of immune responses and immune mechanisms that protect against malaria. With this knowledge, vaccines can be designed against malaria to prevent serious illness and death.