Fluorescence spectrophotometer

这项提议是为购买配备多细胞Peltier和微孔板阅读器的荧光分光光度计申请资金。该仪器将用于需要常规使用灵敏荧光分光光度计的各种研究项目。这些包括研究牛乳铁蛋白的相互作用，开发新的细胞溶解抗菌肽，以及开发独特的检测系统来识别相关的生物分析物。拉瓦尔大学化学系目前只有一个研究级荧光分光光度计，该仪器于2001年从M.Leclerc的加拿大研究主席那里获得CFI资金。为了满足M.Leclerc小组对该仪器的需求，需要全天候使用该仪器。Laval的其他用户，来自申请者小组，偶尔(2%-3%的时间)被Leclerc小组慷慨地授予访问仪器的权限。然而，申请团体在几个项目中开展的新研究活动增加了对荧光分光光度的需求，因此需要购买灵敏的荧光分光光度计。申请书中所述的几个项目的进展因无法定期获得这类文书而严重受阻。

This proposal is to request funding for the purchase of a fluorescence spectrophotometer equipped with a multicell Peltier and a microplate reader. This instrument will be used for a variety of research projects that require routine access to a sensitive fluorescence spectrophotometer. These include studies on the interaction of bovine lactoferricin, the development of novel cytolytic antimicrobial peptides and the development of unique detection systems for identifying relevant biological analytes of interest. There is currently only one research-grade fluorescent spectrophotometer in the Department of Chemistry at Université Laval, an instrument acquired in 2001 with CFI funds from M. Leclerc's Canada Research Chair. The needs for that instrument in M. Leclerc's group require a full time use of that instrument. Other users at Laval, from the groups of the applicants, are occasionally (2-3% of the time) graciously granted access to the instrument by the Leclerc group. However, the increased demand for fluorescence spectrophotometry by the new research activities in several projects by the applicant groups warrant the acquisition of a sensitive fluorescent spectrophotometer. The progress of several projects described in the application is severely impeded by the lack of regular access to such an instrument.