Translating advances in molecular oncology into improved care for patients with haematological malignancies

我的研究目的是为白血病、淋巴瘤、骨髓瘤等血癌患者开发更好的治疗范例，并将其整合到常规实践中。我的研究旨在(I)将一种新的抗癌靶向治疗--Bcl-2抑制剂--纳入常规护理；(Ii)发现解释为什么缓慢生长的淋巴癌转变为迅速致命的淋巴瘤的基因变化；以及(Iii)将新的分子测试整合到急性白血病患者的治疗中。

The purpose of my research is to develop and integrate into routine practice better treatment paradigms for patients with blood cancers – leukaemias, lymphomas, myeloma. My research seeks to (i) bring a new class of anti-cancer targeted therapy, inhibitors of Bcl-2, into routine care; (ii) discover the genetic changes that explain why slow growing lymphoid cancers change into rapidly fatal lymphomas; and (iii) integrate new molecular tests into the management of patients with acute leukaemia.